Atorvastatin EP Impurity D

Name: Atorvastatin EP Impurity D
Brand: Vaqora Chemicals
SKU: VQ-020853

About Atorvastatin EP Impurity D

Listed under CAS 148146-51-4, Atorvastatin EP Impurity D is a pharmacopeial impurity of Atorvastatin available from Vaqora Chemicals. Its molecular formula is C26H22FNO4 and its molecular weight is 431.5 g/mol. Its systematic (IUPAC) name is 3-(4-fluorobenzoyl)-2-(2-methylpropanoyl)-N,3-diphenyloxirane-2-carboxamide. Common synonyms include Atorvastatin Impurity D and Atorvastatin Related Compound D.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This Atorvastatin impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Atorvastatin

View every impurity, metabolite and intermediate we list for Atorvastatin.

Atorvastatin impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Atorvastatin EP Impurity D
Catalogue No.	VQ-020853
CAS Number	148146-51-4
IUPAC name	3-(4-fluorobenzoyl)-2-(2-methylpropanoyl)-N,3-diphenyloxirane-2-carboxamide
Molecular formula	C₂₆H₂₂FNO₄
Molecular weight	431.5 g/mol
Exact mass	431.1533
Grade	Reference Standard
HSN code	38229090
InChIKey	AAEQXEDPVFIFDK-UHFFFAOYSA-N
SMILES	CC(C)C(=O)C1(C(O1)(C2=CC=CC=C2)C(=O)C3=CC=C(C=C3)F)C(=O)NC4=CC=CC=C4
PubChem CID	11976726

Physical properties
Physical form	Solid
LogP (XLogP3)	5.2
H-bond donors / acceptors	1 / 5
TPSA	75.8 Å²
Synonyms	Atorvastatin Impurity D, Atorvastatin Related Compound D, Atorvastatin Acid - Impurity D, Atorvastatin Calcium Related Compound D, 3-((4-Fluorophenyl)carbonyl)-2-(2-methylpropanoyl)-N,3-diphenyloxirane-2-carboxamide, Oxiranecarboxamide, 3-(4-fluorobenzoyl)-2-(2-methyl-1-oxopropyl)-N,3-diphenyl-, 3-[(4-Fluorophenyl)carbonyl]-2-(2-methylpropanoyl)-N,3-diphenyloxirane-2-carboxamide, Atorvastatin calcium trihydrate impurity D, Atorvastatin Epoxydione Impurity, 3-(4-Fluorobenzoyl)-2-isobutyryl-N,3-diphenyloxirane-2-carboxamide, 2-Oxiranecarboxamide, 3-(4-fluorobenzoyl)-2-(2-methyl-1-oxopropyl)-N,3-diphenyl-, Atorvastatin Epoxide

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P321, P330, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Atorvastatin EP Impurity D?

The CAS Registry Number of Atorvastatin EP Impurity D is 148146-51-4. It is also known as Atorvastatin Impurity D, Atorvastatin Related Compound D, Atorvastatin Acid - Impurity D.

What is the molecular formula and molecular weight of Atorvastatin EP Impurity D?

Atorvastatin EP Impurity D has the molecular formula C26H22FNO4 and a molecular weight of 431.5 g/mol. Its IUPAC name is 3-(4-fluorobenzoyl)-2-(2-methylpropanoyl)-N,3-diphenyloxirane-2-carboxamide.

What is Atorvastatin EP Impurity D used for?

Atorvastatin EP Impurity D is supplied as a characterised reference material related to Atorvastatin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Atorvastatin EP Impurity D can I order?

We supply Atorvastatin EP Impurity D in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Atorvastatin EP Impurity D?

Yes. Every lot of Atorvastatin EP Impurity D is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Atorvastatin EP Impurity D be shipped internationally?

Yes. Atorvastatin EP Impurity D is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.