Axitinib-d3

Name: Axitinib-d3
Brand: Vaqora Chemicals
SKU: VQ-043379

About Axitinib-d3

Vaqora Chemicals supplies Axitinib-d3, a stable isotope labelled analogue related to Axitinib registered under CAS number 1126623-89-9. Formula C22H18N4OS, molecular weight 389.5 g/mol. Systematically, it is named 2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]-N-(trideuteriomethyl)benzamide. Alternative names: Axitinib-d3 H2O (N-methyl-d3).

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Axitinib and related analytes in bioanalytical, pharmacokinetic and impurity studies. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Axitinib-d3 in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Axitinib

View every impurity, metabolite and intermediate we list for Axitinib.

Axitinib impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Axitinib-d3
Catalogue No.	VQ-043379
CAS Number	1126623-89-9
IUPAC name	2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]-N-(trideuteriomethyl)benzamide
Molecular formula	C₂₂H₁₈N₄OS
Molecular weight	389.5 g/mol
Exact mass	389.139
Grade	Reference Standard
HSN code	38229090
InChIKey	RITAVMQDGBJQJZ-VOTVRPQJSA-N
SMILES	[2H]C([2H])([2H])NC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=NN3)/C=C/C4=CC=CC=N4
PubChem CID	25213804

Physical properties
Physical form	Solid
LogP (XLogP3)	4.2
H-bond donors / acceptors	2 / 4
TPSA	96 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Axitinib-d3?

The CAS Registry Number of Axitinib-d3 is 1126623-89-9. It is also known as Axitinib-d3 H2O (N-methyl-d3), (E)-N-(methyl-d3)-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide.

What is the molecular formula and molecular weight of Axitinib-d3?

Axitinib-d3 has the molecular formula C22H18N4OS and a molecular weight of 389.5 g/mol. Its IUPAC name is 2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]-N-(trideuteriomethyl)benzamide.

What is Axitinib-d3 used for?

Axitinib-d3 is supplied as a characterised reference material related to Axitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Axitinib-d3 can I order?

We supply Axitinib-d3 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Axitinib-d3?

Yes. Every lot of Axitinib-d3 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Axitinib-d3 be shipped internationally?

Yes. We export Axitinib-d3 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.