Bendamustine Hydrochloride

Name: Bendamustine Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-007340

About Bendamustine Hydrochloride

Listed under CAS 3543-75-7, Bendamustine Hydrochloride is a high-purity reference standard of Bendamustine available from Vaqora Chemicals. The compound has the formula C16H22Cl3N3O2, corresponding to a molecular weight of 394.7 g/mol. The IUPAC name is 4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid. Hydrochloride. Common synonyms include Cytostasan and Ribomustin.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a reference sample of Bendamustine, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Bendamustine Hydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Bendamustine

View every impurity, metabolite and intermediate we list for Bendamustine.

Bendamustine impurities

Specifications & identifiers

Chemical identifiers
Product name	Bendamustine Hydrochloride
Catalogue No.	VQ-007340
CAS Number	3543-75-7
Other CAS	16506-27-7
IUPAC name	4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid;hydrochloride
Molecular formula	C₁₆H₂₂Cl₃N₃O₂
Molecular weight	394.7 g/mol
Exact mass	393.0778
Grade	Reference Standard
HSN code	38229090
InChIKey	ZHSKUOZOLHMKEA-UHFFFAOYSA-N
SMILES	CN1C2=C(C=C(C=C2)N(CCCl)CCCl)N=C1CCCC(=O)O.Cl
PubChem CID	77082

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 4
TPSA	58.4 Å²
Synonyms	5-[Bis(2-chloroethyl)amino]-1-methylbenzimidazole-2-butyric Acid Hydrochloride, Cytostasan, Ribomustin, Treanda, 2-Benzimidazolebutyric acid, 5-[bis(2-chloroethyl)amino]-1-methyl-, monohydrochloride, Bendamustine HCl, Bendamustin hydrochloride, Ribomustine, SyB L-0501, SYBL-0501, 1H-Benzimidazole-2-butanoic acid, 5-(bis(2-chloroethyl)amino)-1-methyl-, monohydrochloride, 2-Benzimidazolinebutryric acid, 1-methyl-5-bis(2-chloroethyl)amino-, hydrochloride

Safety & hazard information (GHS)

Toxic

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H340May cause genetic defects
H350May cause cancer
H351Suspected of causing cancer
H360May damage fertility or the unborn child

Precautionary statements: P203, P264, P270, P280, P301 + P316, P318, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Bendamustine Hydrochloride?

The CAS Registry Number of Bendamustine Hydrochloride is 3543-75-7. It is also known as 5-[Bis(2-chloroethyl)amino]-1-methylbenzimidazole-2-butyric Acid Hydrochloride, Cytostasan, Ribomustin.

What is the molecular formula and molecular weight of Bendamustine Hydrochloride?

Bendamustine Hydrochloride has the molecular formula C16H22Cl3N3O2 and a molecular weight of 394.7 g/mol.

What is Bendamustine Hydrochloride used for?

Bendamustine Hydrochloride is supplied as a characterised reference material related to Bendamustine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Bendamustine Hydrochloride can I order?

We supply Bendamustine Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Bendamustine Hydrochloride?

Yes. Every lot of Bendamustine Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Bendamustine Hydrochloride be shipped internationally?

Yes. Bendamustine Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.