Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[… 1257099-42-5

Name: Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[6-(ethenyloxy)-5-hydroxy[2,2′-bipyrimidin]-4-yl]
Brand: Vaqora Chemicals
SKU: VQ-044040

About Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[6-(ethenyloxy)-5-hydroxy[2,2′-bipyrimidin]-4-yl]

Listed under CAS 1257099-42-5, Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[6-(ethenyloxy)-5-hydroxy[2,2′-bipyrimidin]-4-yl] is a metabolite or degradation product of Bosentan available from Vaqora Chemicals. Formula C20H21N5O4S, molecular weight 427.5 g/mol. Its systematic (IUPAC) name is 4-tert-butyl-N-(6-ethenoxy-5-hydroxy-2-pyrimidin-2-ylpyrimidin-4-yl)benzenesulfonamide.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Bosentan, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[6-(ethenyloxy)-5-hydroxy[2,2′-bipyrimidin]-4-yl] in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Bosentan

View every impurity, metabolite and intermediate we list for Bosentan.

Bosentan impurities

Specifications & identifiers

Chemical identifiers
Product name	Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[6-(ethenyloxy)-5-hydroxy[2,2′-bipyrimidin]-4-yl]
Catalogue No.	VQ-044040
CAS Number	1257099-42-5
IUPAC name	4-tert-butyl-N-(6-ethenoxy-5-hydroxy-2-pyrimidin-2-ylpyrimidin-4-yl)benzenesulfonamide
Molecular formula	C₂₀H₂₁N₅O₄S
Molecular weight	427.5 g/mol
Exact mass	427.1314
Grade	Reference Standard
HSN code	38229090
InChIKey	NVFOHQFYZFTQJU-UHFFFAOYSA-N
SMILES	CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NC2=C(C(=NC(=N2)C3=NC=CC=N3)OC=C)O
PubChem CID	135927706

Physical properties
Physical form	Solid
LogP (XLogP3)	3.1
H-bond donors / acceptors	2 / 9
TPSA	136 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[6-(ethenyloxy)-5-hydroxy[2,2′-bipyrimidin]-4-yl]?

The CAS Registry Number of Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[6-(ethenyloxy)-5-hydroxy[2,2′-bipyrimidin]-4-yl] is 1257099-42-5.

What is the molecular formula and molecular weight of Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[6-(ethenyloxy)-5-hydroxy[2,2′-bipyrimidin]-4-yl]?

Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[6-(ethenyloxy)-5-hydroxy[2,2′-bipyrimidin]-4-yl] has the molecular formula C20H21N5O4S and a molecular weight of 427.5 g/mol. Its IUPAC name is 4-tert-butyl-N-(6-ethenoxy-5-hydroxy-2-pyrimidin-2-ylpyrimidin-4-yl)benzenesulfonamide.

What is Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[6-(ethenyloxy)-5-hydroxy[2,2′-bipyrimidin]-4-yl] used for?

Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[6-(ethenyloxy)-5-hydroxy[2,2′-bipyrimidin]-4-yl] is supplied as a characterised reference material related to Bosentan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[6-(ethenyloxy)-5-hydroxy[2,2′-bipyrimidin]-4-yl] can I order?

We supply Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[6-(ethenyloxy)-5-hydroxy[2,2′-bipyrimidin]-4-yl] in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[6-(ethenyloxy)-5-hydroxy[2,2′-bipyrimidin]-4-yl]?

Yes. Every lot of Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[6-(ethenyloxy)-5-hydroxy[2,2′-bipyrimidin]-4-yl] is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[6-(ethenyloxy)-5-hydroxy[2,2′-bipyrimidin]-4-yl] be shipped internationally?

Yes. We export Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[6-(ethenyloxy)-5-hydroxy[2,2′-bipyrimidin]-4-yl] worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.