Binimetinib Intermediate 2

Name: Binimetinib Intermediate 2
Brand: Vaqora Chemicals
SKU: VQ-013212

About Binimetinib Intermediate 2

Binimetinib Intermediate 2 is a process intermediate or related compound of Binimetinib carrying the CAS registry number 197520-71-1. The compound has the formula C7H2F3NO4, corresponding to a molecular weight of 221.09 g/mol. The IUPAC name is 2,3,4-trifluoro-5-nitrobenzoic acid. Alternative names: 5-Nitro-2,3,4-trifluorobenzoic acid and 2,3,4-Trifluoro-5-nitro-benzoic acid.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Process chemists and analysts use it when developing synthetic routes to Binimetinib, tracking process-related impurities and validating analytical methods. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Binimetinib Intermediate 2 in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Binimetinib

View every impurity, metabolite and intermediate we list for Binimetinib.

Binimetinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Binimetinib Intermediate 2
Catalogue No.	VQ-013212
CAS Number	197520-71-1
IUPAC name	2,3,4-trifluoro-5-nitrobenzoic acid
Molecular formula	C₇H₂F₃NO₄
Molecular weight	221.09 g/mol
Exact mass	220.9936
Grade	Reference Standard
InChIKey	BCMIOBTWFPSPJJ-UHFFFAOYSA-N
SMILES	C1=C(C(=C(C(=C1[N+](=O)[O-])F)F)F)C(=O)O
PubChem CID	15871241

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	1 / 7
TPSA	83.1 Å²
Synonyms	5-Nitro-2,3,4-trifluorobenzoic acid, 2,3,4-Trifluoro-5-nitro-benzoic acid, Benzoic acid, 2,3,4-trifluoro-5-nitro-, 2,3,4-Trifluoro-5-nitro benzoic acid, CS-M0255, 2,3,4-trifluoro-5-nitrobenzoic acid

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H314Causes severe skin burns and eye damage
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P260, P261, P264, P264 + P265, P271, P280, P301 + P330 + P331, P302 + P352, P302 + P361 + P354, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P316, P317, P319, P321, P332 + P317, P337 + P317, P362 + P364, P363, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Binimetinib Intermediate 2?

The CAS Registry Number of Binimetinib Intermediate 2 is 197520-71-1. It is also known as 5-Nitro-2,3,4-trifluorobenzoic acid, 2,3,4-Trifluoro-5-nitro-benzoic acid, Benzoic acid, 2,3,4-trifluoro-5-nitro-.

What is the molecular formula and molecular weight of Binimetinib Intermediate 2?

Binimetinib Intermediate 2 has the molecular formula C7H2F3NO4 and a molecular weight of 221.09 g/mol. Its IUPAC name is 2,3,4-trifluoro-5-nitrobenzoic acid.

What is Binimetinib Intermediate 2 used for?

Binimetinib Intermediate 2 is supplied as a characterised reference material related to Binimetinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Binimetinib Intermediate 2 can I order?

We supply Binimetinib Intermediate 2 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Binimetinib Intermediate 2?

Yes. Every lot of Binimetinib Intermediate 2 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Binimetinib Intermediate 2 be shipped internationally?

Yes. Binimetinib Intermediate 2 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.