Binimetinib Intermediate 4

Name: Binimetinib Intermediate 4
Brand: Vaqora Chemicals
SKU: VQ-013214

About Binimetinib Intermediate 4

Vaqora Chemicals supplies Binimetinib Intermediate 4, a process intermediate or related compound of Binimetinib registered under CAS number 284030-58-6. The compound has the formula C8H6F2N2O4, corresponding to a molecular weight of 232.14 g/mol. Its systematic (IUPAC) name is methyl 4-amino-2,3-difluoro-5-nitrobenzoate. It is also known as methyl 4-amino-2,3-difluoro-5-nitro-benzoate or 4-amino-2,3-difluoro-5-nitrobenzoate.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

It is a process intermediate or related compound in the synthesis of Binimetinib, useful for route development, impurity fate-and-purge studies and analytical method development. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Binimetinib Intermediate 4 is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Binimetinib

View every impurity, metabolite and intermediate we list for Binimetinib.

Binimetinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Binimetinib Intermediate 4
Catalogue No.	VQ-013214
CAS Number	284030-58-6
IUPAC name	methyl 4-amino-2,3-difluoro-5-nitrobenzoate
Molecular formula	C₈H₆F₂N₂O₄
Molecular weight	232.14 g/mol
Exact mass	232.0296
Grade	Reference Standard
HSN code	2933
InChIKey	HOJFIOHGPQOQBF-UHFFFAOYSA-N
SMILES	COC(=O)C1=CC(=C(C(=C1F)F)N)[N+](=O)[O-]
PubChem CID	2759749

Physical properties
Physical form	Solid
LogP (XLogP3)	1.7
H-bond donors / acceptors	1 / 7
TPSA	98.1 Å²
Synonyms	4-Amino-2,3-difluoro-5-nitrobenzoic acid methyl ester, Benzoic acid, 4-amino-2,3-difluoro-5-nitro-, methyl ester, 4-amino-2,3-difluoro-5-nitro-benzoic acid methyl ester, methyl 4-amino-2,3-difluoro-5-nitro-benzoate, 4-amino-2,3-difluoro-5-nitrobenzoate, CS-M0257, Methyl 2-amino-2,3-difluoro-5-nitrobenzoate, Methyl 4-amino-2,3-difluoro-5-nitro-benzoic acid, Benzoic acid,4-aMino-2,3-difluoro-5-nitro-, Methyl ester, Benzoic acid, 4-amino-2,3-difluoro-5-nitro-, methyl ester (9CI, ACI)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 284030-58-6

Methyl 4-amino-2,3-difluoro-5-nitrobenzoate, 97%

CAS: 284030-58-6
Formula: C₈H₆F₂N₂O₄
MW: 232.14 g/mol

VQ-009881

Frequently asked questions

What is the CAS number of Binimetinib Intermediate 4?

The CAS Registry Number of Binimetinib Intermediate 4 is 284030-58-6. It is also known as 4-Amino-2,3-difluoro-5-nitrobenzoic acid methyl ester, Benzoic acid, 4-amino-2,3-difluoro-5-nitro-, methyl ester, 4-amino-2,3-difluoro-5-nitro-benzoic acid methyl ester.

What is the molecular formula and molecular weight of Binimetinib Intermediate 4?

Binimetinib Intermediate 4 has the molecular formula C8H6F2N2O4 and a molecular weight of 232.14 g/mol. Its IUPAC name is methyl 4-amino-2,3-difluoro-5-nitrobenzoate.

What is Binimetinib Intermediate 4 used for?

Binimetinib Intermediate 4 is supplied as a characterised reference material related to Binimetinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Binimetinib Intermediate 4 can I order?

We supply Binimetinib Intermediate 4 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Binimetinib Intermediate 4?

Yes. Every lot of Binimetinib Intermediate 4 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Binimetinib Intermediate 4 be shipped internationally?

Yes. Binimetinib Intermediate 4 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.