Brexpiprazole-d8

Name: Brexpiprazole-d8
Brand: Vaqora Chemicals
SKU: VQ-029503

About Brexpiprazole-d8

Vaqora Chemicals supplies Brexpiprazole-d8, a stable isotope labelled analogue related to Brexpiprazole registered under CAS number 1427049-19-1. Its molecular formula is C25H27N3O2S and its molecular weight is 441.6 g/mol. Systematically, it is named 7-[4-[4-(1-benzothiophen-4-yl)-2,2,3,3,5,5,6,6-octadeuteriopiperazin-1-yl]butoxy]-1H-quinolin-2-one. Alternative names: Brexpiprazole D8 (alkyl-D8) and Brexpiprazole-d8(2,2,3,3,5,5,6,6-d8).

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 5 hazard statements. Review the Safety Data Sheet before use.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Brexpiprazole and related analytes in bioanalytical, pharmacokinetic and impurity studies. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Brexpiprazole-d8 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Brexpiprazole

View every impurity, metabolite and intermediate we list for Brexpiprazole.

Brexpiprazole impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Brexpiprazole-d8
Catalogue No.	VQ-029503
CAS Number	1427049-19-1
IUPAC name	7-[4-[4-(1-benzothiophen-4-yl)-2,2,3,3,5,5,6,6-octadeuteriopiperazin-1-yl]butoxy]-1H-quinolin-2-one
Molecular formula	C₂₅H₂₇N₃O₂S
Molecular weight	441.6 g/mol
Exact mass	441.2326
Grade	Reference Standard
HSN code	38229090
InChIKey	ZKIAIYBUSXZPLP-DHNBGMNGSA-N
SMILES	[2H]C1(C(N(C(C(N1CCCCOC2=CC3=C(C=C2)C=CC(=O)N3)([2H])[2H])([2H])[2H])C4=C5C=CSC5=CC=C4)([2H])[2H])[2H]
PubChem CID	89428953

Physical properties
Physical form	Solid
LogP (XLogP3)	4.7
H-bond donors / acceptors	1 / 5
TPSA	73.1 Å²

Safety & hazard information (GHS)

Toxic

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H351Suspected of causing cancer
H361Suspected of damaging fertility or the unborn child
H362May cause harm to breast-fed children
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P263, P264, P270, P280, P301 + P316, P318, P319, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Brexpiprazole-d8?

The CAS Registry Number of Brexpiprazole-d8 is 1427049-19-1. It is also known as Brexpiprazole D8 (alkyl-D8), Brexpiprazole-d8(2,2,3,3,5,5,6,6-d8), 7-(4-(4-(benzo[b]thiophen-4-yl)piperazin-1-yl-2,2,3,3,5,5,6,6-d8)butoxy)quinolin-2(1H)-one.

What is the molecular formula and molecular weight of Brexpiprazole-d8?

Brexpiprazole-d8 has the molecular formula C25H27N3O2S and a molecular weight of 441.6 g/mol. Its IUPAC name is 7-[4-[4-(1-benzothiophen-4-yl)-2,2,3,3,5,5,6,6-octadeuteriopiperazin-1-yl]butoxy]-1H-quinolin-2-one.

What is Brexpiprazole-d8 used for?

Brexpiprazole-d8 is supplied as a characterised reference material related to Brexpiprazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Brexpiprazole-d8 can I order?

We supply Brexpiprazole-d8 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Brexpiprazole-d8?

Yes. Every lot of Brexpiprazole-d8 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Brexpiprazole-d8 be shipped internationally?

Yes. Brexpiprazole-d8 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.