Bumetanide EP Impurity B

Name: Bumetanide EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-021012

About Bumetanide EP Impurity B

Bumetanide EP Impurity B is a pharmacopeial impurity of Bumetanide carrying the CAS registry number 28328-54-3. Its molecular formula is C13H12N2O5S and its molecular weight is 308.31 g/mol. Its systematic (IUPAC) name is 3-amino-4-phenoxy-5-sulfamoylbenzoic acid. It is also known as Bumetanide - Impurity B or Desbutylbumetanide.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Bumetanide, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Bumetanide

View every impurity, metabolite and intermediate we list for Bumetanide.

Bumetanide impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Bumetanide EP Impurity B
Catalogue No.	VQ-021012
CAS Number	28328-54-3
IUPAC name	3-amino-4-phenoxy-5-sulfamoylbenzoic acid
Molecular formula	C₁₃H₁₂N₂O₅S
Molecular weight	308.31 g/mol
Exact mass	308.0467
Grade	Reference Standard
HSN code	38229090
InChIKey	GVQZPZSQRCXSJI-UHFFFAOYSA-N
SMILES	C1=CC=C(C=C1)OC2=C(C=C(C=C2S(=O)(=O)N)C(=O)O)N
PubChem CID	119927

Physical properties
Physical form	Solid
LogP (XLogP3)	0.9
H-bond donors / acceptors	3 / 7
TPSA	141 Å²
Synonyms	Bumetanide EP Impurity B, Bumetanide USP RC A, Desbutyl Bumetanide, Bumetanide - Impurity B, Desbutylbumetanide, 3-Amino-5-(aminosulphonyl)-4-phenoxybenzoic acid, Benzoic acid, 3-amino-5-(aminosulfonyl)-4-phenoxy-, Desbutyl Bumetanide, 3-Amino-4-phenoxy-5-sulfamoyl-benzoic acid, 3-Amino-4-phenoxy-5-sulfamoylbenoic acid, 5-Amino-3-aminosulfony-4-phenoxybenzoic acid, Benzoic acid,3-amino-5-(aminosulfonyl)-4-phenoxy-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Bumetanide EP Impurity B?

The CAS Registry Number of Bumetanide EP Impurity B is 28328-54-3. It is also known as Bumetanide EP Impurity B, Bumetanide USP RC A, Desbutyl Bumetanide.

What is the molecular formula and molecular weight of Bumetanide EP Impurity B?

Bumetanide EP Impurity B has the molecular formula C13H12N2O5S and a molecular weight of 308.31 g/mol. Its IUPAC name is 3-amino-4-phenoxy-5-sulfamoylbenzoic acid.

What is Bumetanide EP Impurity B used for?

Bumetanide EP Impurity B is supplied as a characterised reference material related to Bumetanide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Bumetanide EP Impurity B can I order?

We supply Bumetanide EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Bumetanide EP Impurity B?

Yes. Every lot of Bumetanide EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Bumetanide EP Impurity B be shipped internationally?

Yes. Bumetanide EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.