Buprenorphine

Name: Buprenorphine
Brand: Vaqora Chemicals
SKU: VQ-007362

About Buprenorphine

Buprenorphine is a high-purity reference standard of Buprenorphine carrying the CAS registry number 52485-79-7. Its molecular formula is C29H41NO4 and its molecular weight is 467.6 g/mol. It is also known as Brixadi or Buprecare.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 7 hazard statements. Review the Safety Data Sheet before use.

Laboratories use this Buprenorphine standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Buprenorphine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Buprenorphine

View every impurity, metabolite and intermediate we list for Buprenorphine.

Buprenorphine impurities

Specifications & identifiers

Chemical identifiers
Product name	Buprenorphine
Catalogue No.	VQ-007362
CAS Number	52485-79-7
Other CAS	53152-21-9
IUPAC name	(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Molecular formula	C₂₉H₄₁NO₄
Molecular weight	467.6 g/mol
Exact mass	467.3036
Grade	Reference Standard
HSN code	38229090
InChIKey	RMRJXGBAOAMLHD-IHFGGWKQSA-N
SMILES	C[C@]([C@H]1C[C@@]23CC[C@@]1([C@H]4[C@@]25CCN([C@@H]3CC6=C5C(=C(C=C6)O)O4)CC7CC7)OC)(C(C)(C)C)O
PubChem CID	644073

Physical properties
Physical form	Solid
LogP (XLogP3)	5
H-bond donors / acceptors	2 / 5
TPSA	62.2 Å²
Synonyms	Brixadi, Buprecare, Buprenorfine, Buvidal, Subutex, Temgesic, Transtec, Buprenophine, (-)-buprenorphine, buprenorphin, Hapoctasin, Sevodyne

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H361Suspected of damaging fertility or the unborn child
H362May cause harm to breast-fed children

Precautionary statements: P203, P260, P261, P263, P264, P264 + P265, P270, P271, P280, P301 + P316, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Buprenorphine?

The CAS Registry Number of Buprenorphine is 52485-79-7. It is also known as Brixadi, Buprecare, Buprenorfine.

What is the molecular formula and molecular weight of Buprenorphine?

Buprenorphine has the molecular formula C29H41NO4 and a molecular weight of 467.6 g/mol.

What is Buprenorphine used for?

Buprenorphine is supplied as a characterised reference material related to Buprenorphine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Buprenorphine can I order?

We supply Buprenorphine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Buprenorphine?

Yes. Every lot of Buprenorphine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Buprenorphine be shipped internationally?

Yes. Buprenorphine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.