Buprenorphine Hydrochloride

Name: Buprenorphine Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-007363

About Buprenorphine Hydrochloride

Listed under CAS 53152-21-9, Buprenorphine Hydrochloride is a high-purity reference standard of Buprenorphine available from Vaqora Chemicals. The compound has the formula C29H42ClNO4, corresponding to a molecular weight of 504.1 g/mol. Common synonyms include Buprederm and Buprenex.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Laboratories use this Buprenorphine standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Buprenorphine Hydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Buprenorphine

View every impurity, metabolite and intermediate we list for Buprenorphine.

Buprenorphine impurities

Specifications & identifiers

Chemical identifiers
Product name	Buprenorphine Hydrochloride
Catalogue No.	VQ-007363
CAS Number	53152-21-9
Other CAS	52485-79-7
IUPAC name	(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol;hydrochloride
Molecular formula	C₂₉H₄₂ClNO₄
Molecular weight	504.1 g/mol
Exact mass	503.2802
Grade	Reference Standard
HSN code	38229090
InChIKey	UAIXRPCCYXNJMQ-RZIPZOSSSA-N
SMILES	C[C@]([C@H]1C[C@@]23CC[C@@]1([C@H]4[C@@]25CCN([C@@H]3CC6=C5C(=C(C=C6)O)O4)CC7CC7)OC)(C(C)(C)C)O.Cl
PubChem CID	3033050

Physical properties
Physical form	Solid
H-bond donors / acceptors	3 / 5
TPSA	62.2 Å²
Synonyms	Buprederm, Buprenex, Buprex, Lepetan, MR 56, NIH 8805, Sixmo, UM 952, Vetergesic, Buprenorphine Hcl, Anorfin, Probuphine

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H302Harmful if swallowed
H317May cause an allergic skin reaction
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H336May cause drowsiness or dizziness
H361Suspected of damaging fertility or the unborn child
H362May cause harm to breast-fed children
H370Causes damage to organs
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P203, P233, P260, P261, P263, P264, P270, P271, P272, P273, P280, P284, P301 + P316, P301 + P317, P302 + P352, P304 + P340, P308 + P316, P318, P319, P321, P330, P333 + P317, P342 + P316, P362 + P364

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Buprenorphine Hydrochloride?

The CAS Registry Number of Buprenorphine Hydrochloride is 53152-21-9. It is also known as Buprederm, Buprenex, Buprex.

What is the molecular formula and molecular weight of Buprenorphine Hydrochloride?

Buprenorphine Hydrochloride has the molecular formula C29H42ClNO4 and a molecular weight of 504.1 g/mol.

What is Buprenorphine Hydrochloride used for?

Buprenorphine Hydrochloride is supplied as a characterised reference material related to Buprenorphine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Buprenorphine Hydrochloride can I order?

We supply Buprenorphine Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Buprenorphine Hydrochloride?

Yes. Every lot of Buprenorphine Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Buprenorphine Hydrochloride be shipped internationally?

Yes. Buprenorphine Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.