Cabozantinib 6-Hydroxy impurity

Name: Cabozantinib 6-Hydroxy impurity
Brand: Vaqora Chemicals
SKU: VQ-020692

About Cabozantinib 6-Hydroxy impurity

Vaqora Chemicals supplies Cabozantinib 6-Hydroxy impurity, a metabolite or degradation product of Cabozantinib registered under CAS number 1628530-47-1. Its molecular formula is C27H22FN3O5 and its molecular weight is 487.5 g/mol. Its systematic (IUPAC) name is 1-N'-(4-fluorophenyl)-1-N-[4-(6-hydroxy-7-methoxyquinolin-4-yl)oxyphenyl]cyclopropane-1,1-dicarboxamide. It is also known as Dimethyl cabozantinib or Cabozantinib metabolite M15.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Cabozantinib, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Cabozantinib 6-Hydroxy impurity is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Cabozantinib

View every impurity, metabolite and intermediate we list for Cabozantinib.

Cabozantinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Cabozantinib 6-Hydroxy impurity
Catalogue No.	VQ-020692
CAS Number	1628530-47-1
IUPAC name	1-N'-(4-fluorophenyl)-1-N-[4-(6-hydroxy-7-methoxyquinolin-4-yl)oxyphenyl]cyclopropane-1,1-dicarboxamide
Molecular formula	C₂₇H₂₂FN₃O₅
Molecular weight	487.5 g/mol
Exact mass	487.1543
Grade	Reference Standard
HSN code	38229090
InChIKey	NHMICDOYSFGBAB-UHFFFAOYSA-N
SMILES	COC1=CC2=NC=CC(=C2C=C1O)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F
PubChem CID	86269671

Physical properties
Physical form	Solid
LogP (XLogP3)	5.1
H-bond donors / acceptors	3 / 7
TPSA	110 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cabozantinib 6-Hydroxy impurity?

The CAS Registry Number of Cabozantinib 6-Hydroxy impurity is 1628530-47-1. It is also known as Dimethyl cabozantinib, Cabozantinib metabolite M15.

What is the molecular formula and molecular weight of Cabozantinib 6-Hydroxy impurity?

Cabozantinib 6-Hydroxy impurity has the molecular formula C27H22FN3O5 and a molecular weight of 487.5 g/mol. Its IUPAC name is 1-N'-(4-fluorophenyl)-1-N-[4-(6-hydroxy-7-methoxyquinolin-4-yl)oxyphenyl]cyclopropane-1,1-dicarboxamide.

What is Cabozantinib 6-Hydroxy impurity used for?

Cabozantinib 6-Hydroxy impurity is supplied as a characterised reference material related to Cabozantinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cabozantinib 6-Hydroxy impurity can I order?

We supply Cabozantinib 6-Hydroxy impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cabozantinib 6-Hydroxy impurity?

Yes. Every lot of Cabozantinib 6-Hydroxy impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cabozantinib 6-Hydroxy impurity be shipped internationally?

Yes. We export Cabozantinib 6-Hydroxy impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.