Capecitabine EP Impurity C

Name: Capecitabine EP Impurity C
Brand: Vaqora Chemicals
SKU: VQ-006286

About Capecitabine EP Impurity C

Listed under CAS 161599-46-8, Capecitabine EP Impurity C is a pharmacopeial impurity of Capecitabine available from Vaqora Chemicals at a purity of 99.86%. With the molecular formula C13H16FN3O6, it has a molar mass of 329.28 g/mol. Its systematic (IUPAC) name is [(2R,3R,4R,5R)-4-acetyloxy-5-(4-amino-5-fluoro-2-oxopyrimidin-1-yl)-2-methyloxolan-3-yl] acetate. It is also known as 2',3'-Di-O-acetyl-5'-deoxy-5-fluorocytidine or 5'-Deoxy-5-fluoro-cytidine 2',3'-Diacetate.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Capecitabine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Capecitabine EP Impurity C is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Capecitabine

View every impurity, metabolite and intermediate we list for Capecitabine.

Capecitabine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Capecitabine EP Impurity C
Catalogue No.	VQ-006286
CAS Number	161599-46-8
Other CAS	880633-96-5
IUPAC name	[(2R,3R,4R,5R)-4-acetyloxy-5-(4-amino-5-fluoro-2-oxopyrimidin-1-yl)-2-methyloxolan-3-yl] acetate
Molecular formula	C₁₃H₁₆FN₃O₆
Molecular weight	329.28 g/mol
Exact mass	329.1023
Grade	Reference Standard
Purity / assay	99.86%
HSN code	38229090
InChIKey	NWJBWNIUGNXJGO-RPULLILYSA-N
SMILES	C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=C(C(=NC2=O)N)F)OC(=O)C)OC(=O)C
PubChem CID	11809635

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.7
H-bond donors / acceptors	1 / 7
TPSA	121 Å²
Synonyms	2',3'-Di-O-acetyl-5'-deoxy-5-fluorocytidine, 5'-Deoxy-5-fluoro-cytidine 2',3'-Diacetate, Capecitabine Diacetyl Amino Impurity, 2',3'-Di-O-acetyl-5-fluoro-5'-deoxycytidine, 5'-Deoxy-2',3'-di-O-acetyl-5-fluorocytidine, Cytidine, 5'-deoxy-5-fluoro-, 2',3'-diacetate, 2`,3`-di-O-acetyl-5`-deoxy-5-fluorocytidin, 2,3-Di-O-Acetyl-5-Deoxy-5-Fuluro-D-Cytidine, 2',3'-Di-O-acetyl-5'-deoxy-5-fluoro-D-cytidine, 2',3'-Di-O-acetyl-5'-deoxy-5-fuluro-D-cytidine, 2', 3'-Di-O-acetyl-5'-Deoxy-5-Fluoro-D-Cytidine, 1-(2,3-Di-O-acetyl-5-deoxy-beta-D-ribofuranosyl)-4-amino-5-fluoropyrimidin-2(1H)-one

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H341Suspected of causing genetic defects
H350May cause cancer
H351Suspected of causing cancer
H360May damage fertility or the unborn child
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P203, P264, P264 + P265, P273, P280, P302 + P352, P305 + P351 + P338, P318, P321, P332 + P317, P337 + P317, P362 + P364, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Capecitabine EP Impurity C?

The CAS Registry Number of Capecitabine EP Impurity C is 161599-46-8. It is also known as 2',3'-Di-O-acetyl-5'-deoxy-5-fluorocytidine, 5'-Deoxy-5-fluoro-cytidine 2',3'-Diacetate, Capecitabine Diacetyl Amino Impurity.

What is the molecular formula and molecular weight of Capecitabine EP Impurity C?

Capecitabine EP Impurity C has the molecular formula C13H16FN3O6 and a molecular weight of 329.28 g/mol. Its IUPAC name is [(2R,3R,4R,5R)-4-acetyloxy-5-(4-amino-5-fluoro-2-oxopyrimidin-1-yl)-2-methyloxolan-3-yl] acetate.

What is Capecitabine EP Impurity C used for?

Capecitabine EP Impurity C is supplied as a characterised reference material related to Capecitabine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Capecitabine EP Impurity C can I order?

We supply Capecitabine EP Impurity C in Reference Standard (99.86%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Capecitabine EP Impurity C?

Yes. Every lot of Capecitabine EP Impurity C is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Capecitabine EP Impurity C be shipped internationally?

Yes. Capecitabine EP Impurity C is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.