Chlormadinone Acetate EP Impurity A (Free Bas… 2477-73-8

Name: Chlormadinone Acetate EP Impurity A (Free Base)
Brand: Vaqora Chemicals
SKU: VQ-022144

About Chlormadinone Acetate EP Impurity A (Free Base)

Vaqora Chemicals supplies Chlormadinone Acetate EP Impurity A (Free Base), a pharmacopeial impurity of Chlormadinone Acetate registered under CAS number 2477-73-8. The compound has the formula C23H31ClO4, corresponding to a molecular weight of 406.9 g/mol. Common synonyms include 6α-Chloro-17-acetoxy Progesterone and Chlormadinone Acetate EP Impurity A.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Chlormadinone Acetate to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Chlormadinone Acetate EP Impurity A (Free Base) in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Chlormadinone Acetate

View every impurity, metabolite and intermediate we list for Chlormadinone Acetate.

Chlormadinone Acetate impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Chlormadinone Acetate EP Impurity A (Free Base)
Catalogue No.	VQ-022144
CAS Number	2477-73-8
IUPAC name	[(6S,8R,9S,10R,13S,14S,17R)-17-acetyl-6-chloro-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate
Molecular formula	C₂₃H₃₁ClO₄
Molecular weight	406.9 g/mol
Exact mass	406.1911
Grade	Reference Standard
HSN code	38229090
InChIKey	DCVGANSDLNPXGO-WXLIAARGSA-N
SMILES	CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2C[C@@H](C4=CC(=O)CC[C@]34C)Cl)C)OC(=O)C
PubChem CID	200665

Physical properties
Physical form	Solid
LogP (XLogP3)	3.7
H-bond donors / acceptors	0 / 4
TPSA	60.4 Å²
Synonyms	6α-Chloro-17-acetoxy Progesterone, Chlormadinone Acetate EP Impurity A, Hydromadinone acetate, Progesterone, 6alpha-chloro-17-hydroxy-, acetate, 6-alpha-Chloro-17-hydroxypregn-4-ene-3,20-dione acetate, (6alpha)-17-(Acetyloxy)-6-chloropregn-4-ene-3,20-dione, Pregn-4-ene-3,20-dione, 6alpha-chloro-17-hydroxy-, acetate, Pregn-4-ene-3,20-dione, 17-(acetyloxy)-6-chloro-, (6alpha)-, pregn-4-ene-3,20-dione, 17-(acetyloxy)-6-chloro-, (6 alpha)-, 6-Chloro-17-acetoxyprogesterone, 6alpha-Chloro-17-acetoxyprogesterone, 6a-Chloro-17-acetoxy Progesterone

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H351Suspected of causing cancer
H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Chlormadinone Acetate EP Impurity A (Free Base)?

The CAS Registry Number of Chlormadinone Acetate EP Impurity A (Free Base) is 2477-73-8. It is also known as 6α-Chloro-17-acetoxy Progesterone, Chlormadinone Acetate EP Impurity A, Hydromadinone acetate.

What is the molecular formula and molecular weight of Chlormadinone Acetate EP Impurity A (Free Base)?

Chlormadinone Acetate EP Impurity A (Free Base) has the molecular formula C23H31ClO4 and a molecular weight of 406.9 g/mol. Its IUPAC name is [(6S,8R,9S,10R,13S,14S,17R)-17-acetyl-6-chloro-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate.

What is Chlormadinone Acetate EP Impurity A (Free Base) used for?

Chlormadinone Acetate EP Impurity A (Free Base) is supplied as a characterised reference material related to Chlormadinone Acetate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Chlormadinone Acetate EP Impurity A (Free Base) can I order?

We supply Chlormadinone Acetate EP Impurity A (Free Base) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Chlormadinone Acetate EP Impurity A (Free Base)?

Yes. Every lot of Chlormadinone Acetate EP Impurity A (Free Base) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Chlormadinone Acetate EP Impurity A (Free Base) be shipped internationally?

Yes. Chlormadinone Acetate EP Impurity A (Free Base) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.