Chlorphenamine EP Impurity D

Name: Chlorphenamine EP Impurity D
Brand: Vaqora Chemicals
SKU: VQ-022151

About Chlorphenamine EP Impurity D

Chlorphenamine EP Impurity D (CAS 65676-21-3) is a pharmacopeial impurity of Chlorpheniramine offered by Vaqora Chemicals. The compound has the formula C17H18ClN3, corresponding to a molecular weight of 299.8 g/mol. The IUPAC name is 2-(4-chlorophenyl)-4-(dimethylamino)-2-pyridin-2-ylbutanenitrile. It is also known as Chlorpheniramine Nitrile or Chlorpheniramine EP Impurity D.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 1 hazard statement. Review the Safety Data Sheet before use.

As a characterised impurity of Chlorpheniramine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Chlorphenamine EP Impurity D in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Chlorpheniramine

View every impurity, metabolite and intermediate we list for Chlorpheniramine.

Chlorpheniramine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Chlorphenamine EP Impurity D
Catalogue No.	VQ-022151
CAS Number	65676-21-3
IUPAC name	2-(4-chlorophenyl)-4-(dimethylamino)-2-pyridin-2-ylbutanenitrile
Molecular formula	C₁₇H₁₈ClN₃
Molecular weight	299.8 g/mol
Exact mass	299.1189
Grade	Reference Standard
HSN code	38229090
InChIKey	XWFSLFHFPQWKNV-UHFFFAOYSA-N
SMILES	CN(C)CCC(C#N)(C1=CC=C(C=C1)Cl)C2=CC=CC=N2
PubChem CID	103434

Physical properties
Physical form	Solid
LogP (XLogP3)	3.1
H-bond donors / acceptors	0 / 3
TPSA	39.9 Å²
Synonyms	Chlorpheniramine Nitrile, Chlorpheniramine EP Impurity D, Chlorphenamine Maleate - Impurity D (Freebase), alpha-(4-Chlorophenyl)-alpha-(2-(dimethylamino)ethyl)-2-pyridineacetonitrile, alpha-(4-Chlorophenyl)-alpha-(2-(dimethylamino)ethyl)pyridine-2-acetonitrile, 2-(4-chlorophenyl)-4-(dimethylamino)-2-(2-pyridyl)butanenitrile, (2RS)-2-(4-chlorophenyl)-4-(dimethylamino)-2-(pyridin-2-yl)butanenitrile, a-( p-Chlorophenyl)-a-[2-(dimethylamino)ethyl]-2-pyridineacetoni trile, a-(4-Chlorophenyl)-a-[2-(dimethylamino)ethyl]-2-pyridineacetonitrile

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements: P264, P270, P301 + P316, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Chlorphenamine EP Impurity D?

The CAS Registry Number of Chlorphenamine EP Impurity D is 65676-21-3. It is also known as Chlorpheniramine Nitrile, Chlorpheniramine EP Impurity D, Chlorphenamine Maleate - Impurity D (Freebase).

What is the molecular formula and molecular weight of Chlorphenamine EP Impurity D?

Chlorphenamine EP Impurity D has the molecular formula C17H18ClN3 and a molecular weight of 299.8 g/mol. Its IUPAC name is 2-(4-chlorophenyl)-4-(dimethylamino)-2-pyridin-2-ylbutanenitrile.

What is Chlorphenamine EP Impurity D used for?

Chlorphenamine EP Impurity D is supplied as a characterised reference material related to Chlorpheniramine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Chlorphenamine EP Impurity D can I order?

We supply Chlorphenamine EP Impurity D in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Chlorphenamine EP Impurity D?

Yes. Every lot of Chlorphenamine EP Impurity D is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Chlorphenamine EP Impurity D be shipped internationally?

Yes. Chlorphenamine EP Impurity D is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.