Cimetidine-D3

Name: Cimetidine-D3
Brand: Vaqora Chemicals
SKU: VQ-036309

About Cimetidine-D3

Vaqora Chemicals supplies Cimetidine-D3, a stable isotope labelled analogue related to Cimetidine registered under CAS number 1185237-29-9. Formula C10H16N6S, molecular weight 255.36 g/mol. The IUPAC name is 1-cyano-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]-2-(trideuteriomethyl)guanidine. Common synonyms include cimetidine-d3 (n-methyl-d3) and TMID-1110.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Cimetidine

View every impurity, metabolite and intermediate we list for Cimetidine.

Cimetidine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Cimetidine-D3
Catalogue No.	VQ-036309
CAS Number	1185237-29-9
IUPAC name	1-cyano-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]-2-(trideuteriomethyl)guanidine
Molecular formula	C₁₀H₁₆N₆S
Molecular weight	255.36 g/mol
Exact mass	255.1345
Grade	Reference Standard
HSN code	38229090
InChIKey	AQIXAKUUQRKLND-BMSJAHLVSA-N
SMILES	[2H]C([2H])([2H])N=C(NCCSCC1=C(NC=N1)C)NC#N
PubChem CID	136257836

Physical properties
Physical form	Solid
LogP (XLogP3)	0.4
H-bond donors / acceptors	3 / 4
TPSA	114 Å²

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H351Suspected of causing cancer
H360May damage fertility or the unborn child

Precautionary statements: P203, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cimetidine-D3?

The CAS Registry Number of Cimetidine-D3 is 1185237-29-9. It is also known as cimetidine-d3 (n-methyl-d3), TMID-1110, 2-cyano-1-(methyl-d3)-3-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)guanidine.

What is the molecular formula and molecular weight of Cimetidine-D3?

Cimetidine-D3 has the molecular formula C10H16N6S and a molecular weight of 255.36 g/mol. Its IUPAC name is 1-cyano-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]-2-(trideuteriomethyl)guanidine.

What is Cimetidine-D3 used for?

Cimetidine-D3 is supplied as a characterised reference material related to Cimetidine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cimetidine-D3 can I order?

We supply Cimetidine-D3 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cimetidine-D3?

Yes. Every lot of Cimetidine-D3 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cimetidine-D3 be shipped internationally?

Yes. Cimetidine-D3 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.