Citric-2,2,4,4-d4 Acid

Name: Citric-2,2,4,4-d4 Acid
Brand: Vaqora Chemicals
SKU: VQ-041151

About Citric-2,2,4,4-d4 Acid

Citric-2,2,4,4-d4 Acid (CAS 147664-83-3) is a stable isotope labelled analogue related to Citric acid offered by Vaqora Chemicals. With the molecular formula C6H8O7, it has a molar mass of 196.15 g/mol. Systematically, it is named 1,1,3,3-tetradeuterio-2-hydroxypropane-1,2,3-tricarboxylic acid. Alternative names: Citric Acid-2,2,4,4-d4 and citric acid-d4.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Citric acid

View every impurity, metabolite and intermediate we list for Citric acid.

Citric acid impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Citric-2,2,4,4-d4 Acid
Catalogue No.	VQ-041151
CAS Number	147664-83-3
IUPAC name	1,1,3,3-tetradeuterio-2-hydroxypropane-1,2,3-tricarboxylic acid
Molecular formula	C₆H₈O₇
Molecular weight	196.15 g/mol
Exact mass	196.0521
Grade	Reference Standard
HSN code	38229090
InChIKey	KRKNYBCHXYNGOX-LNLMKGTHSA-N
SMILES	[2H]C([2H])(C(=O)O)C(C(=O)O)(C([2H])([2H])C(=O)O)O
PubChem CID	16213286

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.7
H-bond donors / acceptors	4 / 7
TPSA	132 Å²
Synonyms	Citric Acid-2,2,4,4-d4, 2-Hydroxy(~2~H_4_)propane-1,2,3-tricarboxylic acid, citric acid-d4, 1,2,3-Propane-1,1,3,3-d4-tricarboxylic acid, 2-hydroxy- (9CI), Citric acid-2,2,4,4-d, TMID-1023, 2-hydroxy((2)H4)propane-1,2,3-tricarboxylic acid

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P354 + P338, P317, P319, P321, P332 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Citric-2,2,4,4-d4 Acid?

The CAS Registry Number of Citric-2,2,4,4-d4 Acid is 147664-83-3. It is also known as Citric Acid-2,2,4,4-d4, 2-Hydroxy(~2~H_4_)propane-1,2,3-tricarboxylic acid, citric acid-d4.

What is the molecular formula and molecular weight of Citric-2,2,4,4-d4 Acid?

Citric-2,2,4,4-d4 Acid has the molecular formula C6H8O7 and a molecular weight of 196.15 g/mol. Its IUPAC name is 1,1,3,3-tetradeuterio-2-hydroxypropane-1,2,3-tricarboxylic acid.

What is Citric-2,2,4,4-d4 Acid used for?

Citric-2,2,4,4-d4 Acid is supplied as a characterised reference material related to Citric acid. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Citric-2,2,4,4-d4 Acid can I order?

We supply Citric-2,2,4,4-d4 Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Citric-2,2,4,4-d4 Acid?

Yes. Every lot of Citric-2,2,4,4-d4 Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Citric-2,2,4,4-d4 Acid be shipped internationally?

Yes. Citric-2,2,4,4-d4 Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.