Clobetasol Propionate

Name: Clobetasol Propionate
Brand: Vaqora Chemicals
SKU: VQ-022220

About Clobetasol Propionate

Clobetasol Propionate (CAS 25122-46-7) is a high-purity reference standard of Clobetasol offered by Vaqora Chemicals. With the molecular formula C25H32ClFO5, it has a molar mass of 467.0 g/mol. It is also known as Clobetasol 17-Propionate or Dermovate.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this Clobetasol standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Clobetasol

View every impurity, metabolite and intermediate we list for Clobetasol.

Clobetasol impurities

Specifications & identifiers

Chemical identifiers
Product name	Clobetasol Propionate
Catalogue No.	VQ-022220
CAS Number	25122-46-7
IUPAC name	[(8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
Molecular formula	C₂₅H₃₂ClFO₅
Molecular weight	467 g/mol
Exact mass	466.1922
Grade	Reference Standard
HSN code	38229090
InChIKey	CBGUOGMQLZIXBE-XGQKBEPLSA-N
SMILES	CCC(=O)O[C@@]1([C@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)O)C)C)C(=O)CCl
PubChem CID	32798

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	1 / 6
TPSA	80.7 Å²
Synonyms	Clobetasol 17-Propionate, Dermovate, Temovate, Embeline, Embeline E, Temovate E, Olux-E, CCI 4725, GR 2/925, clobetasol 17-propanoate, Olux E, Dovate

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H360May damage fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P203, P260, P261, P264, P264 + P265, P271, P273, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Clobetasol Propionate?

The CAS Registry Number of Clobetasol Propionate is 25122-46-7. It is also known as Clobetasol 17-Propionate, Dermovate, Temovate.

What is the molecular formula and molecular weight of Clobetasol Propionate?

Clobetasol Propionate has the molecular formula C25H32ClFO5 and a molecular weight of 467 g/mol.

What is Clobetasol Propionate used for?

Clobetasol Propionate is supplied as a characterised reference material related to Clobetasol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Clobetasol Propionate can I order?

We supply Clobetasol Propionate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Clobetasol Propionate?

Yes. Every lot of Clobetasol Propionate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Clobetasol Propionate be shipped internationally?

Yes. Clobetasol Propionate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.