Clobetasone Butyrate

Name: Clobetasone Butyrate
Brand: Vaqora Chemicals
SKU: VQ-022226

About Clobetasone Butyrate

Vaqora Chemicals supplies Clobetasone Butyrate, an impurity of Clobetasone registered under CAS number 25122-57-0. With the molecular formula C26H32ClFO5, it has a molar mass of 479.0 g/mol. It is also known as Clobetasone 17-butyrate or Eumovate.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Clobetasone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Clobetasone

View every impurity, metabolite and intermediate we list for Clobetasone.

Clobetasone impurities

Specifications & identifiers

Chemical identifiers
Product name	Clobetasone Butyrate
Catalogue No.	VQ-022226
CAS Number	25122-57-0
IUPAC name	[(8S,9R,10S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-10,13,16-trimethyl-3,11-dioxo-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-17-yl] butanoate
Molecular formula	C₂₆H₃₂ClFO₅
Molecular weight	479 g/mol
Exact mass	478.1922
Grade	Reference Standard
HSN code	38229090
InChIKey	FBRAWBYQGRLCEK-AVVSTMBFSA-N
SMILES	CCCC(=O)O[C@@]1([C@H](C[C@@H]2[C@@]1(CC(=O)[C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)C)C)C(=O)CCl
PubChem CID	71386

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	0 / 6
TPSA	77.5 Å²
Synonyms	Clobetasone 17-butyrate, Eumovate, Emovate, Kindavate, Molivate, CCI 5537, SN 203, CCI-5537, Clobavate, Cloburate, Cloburate-n, Eumovate n

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H351Suspected of causing cancer

Precautionary statements: P203, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Clobetasone Butyrate?

The CAS Registry Number of Clobetasone Butyrate is 25122-57-0. It is also known as Clobetasone 17-butyrate, Eumovate, Emovate.

What is the molecular formula and molecular weight of Clobetasone Butyrate?

Clobetasone Butyrate has the molecular formula C26H32ClFO5 and a molecular weight of 479 g/mol. Its IUPAC name is [(8S,9R,10S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-10,13,16-trimethyl-3,11-dioxo-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-17-yl] butanoate.

What is Clobetasone Butyrate used for?

Clobetasone Butyrate is supplied as a characterised reference material related to Clobetasone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Clobetasone Butyrate can I order?

We supply Clobetasone Butyrate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Clobetasone Butyrate?

Yes. Every lot of Clobetasone Butyrate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Clobetasone Butyrate be shipped internationally?

Yes. Clobetasone Butyrate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.