Clobetasone Butyrate EP Impurity A

Name: Clobetasone Butyrate EP Impurity A
Brand: Vaqora Chemicals
SKU: VQ-025030

About Clobetasone Butyrate EP Impurity A

Clobetasone Butyrate EP Impurity A is a pharmacopeial impurity of Clobetasone butyrate carrying the CAS registry number 54063-32-0. Formula C22H26ClFO4, molecular weight 408.9 g/mol. Alternative names: Clobetasone and Clobetasone utyrate EP Impurity A.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Clobetasone butyrate to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Clobetasone butyrate

View every impurity, metabolite and intermediate we list for Clobetasone butyrate.

Clobetasone butyrate impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Clobetasone Butyrate EP Impurity A
Catalogue No.	VQ-025030
CAS Number	54063-32-0
IUPAC name	(8S,9R,10S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-17-hydroxy-10,13,16-trimethyl-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthrene-3,11-dione
Molecular formula	C₂₂H₂₆ClFO₄
Molecular weight	408.9 g/mol
Exact mass	408.1504
Grade	Reference Standard
HSN code	38229090
InChIKey	XXIFVOHLGBURIG-OZCCCYNHSA-N
SMILES	C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3(C(=O)C[C@@]2([C@]1(C(=O)CCl)O)C)F)C
PubChem CID	71387

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	1 / 5
TPSA	71.4 Å²
Synonyms	Clobetasone, Clobetasone utyrate EP Impurity A, Clobetasone Butyrate - Impurity A, 21-Chlor-9-fluor-17-hydroxy-16beta-methyl-1,4-pregnadien-3,11,20-trion, 21-Chloro-11-dehydrobetamethasone, Pregna-1,4-diene-3,11,20-trione, 21-chloro-9-fluoro-17-hydroxy-16-methyl-, (16.beta.)-, (16.beta.)-21-Chloro-9-fluoro-17-hydroxy-16-methylpregna-1,4-diene-3,11,20-trione, (16beta)-21-Chloro-9-fluoro-17-hydroxy-16-methylpregna-1,4-diene-3,11,20-trione, Pregna-1,4-diene-3,11,20-trione, 21-chloro-9-fluoro-17-hydroxy-16-methyl-, (16beta)-, 21-chloro-9-fluoro-17-hydroxy-16, A-methylpregna-1,4-diene-3,11,20-trione (clobetasone), 21-chloro-9alpha-fluoro-17alpha-hydroxy-16beta-methylpregna-1,4-diene-3,11,20-trione

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Clobetasone Butyrate EP Impurity A?

The CAS Registry Number of Clobetasone Butyrate EP Impurity A is 54063-32-0. It is also known as Clobetasone, Clobetasone utyrate EP Impurity A, Clobetasone Butyrate - Impurity A.

What is the molecular formula and molecular weight of Clobetasone Butyrate EP Impurity A?

Clobetasone Butyrate EP Impurity A has the molecular formula C22H26ClFO4 and a molecular weight of 408.9 g/mol. Its IUPAC name is (8S,9R,10S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-17-hydroxy-10,13,16-trimethyl-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthrene-3,11-dione.

What is Clobetasone Butyrate EP Impurity A used for?

Clobetasone Butyrate EP Impurity A is supplied as a characterised reference material related to Clobetasone butyrate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Clobetasone Butyrate EP Impurity A can I order?

We supply Clobetasone Butyrate EP Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Clobetasone Butyrate EP Impurity A?

Yes. Every lot of Clobetasone Butyrate EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Clobetasone Butyrate EP Impurity A be shipped internationally?

Yes. We export Clobetasone Butyrate EP Impurity A worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.