Closantel EP Impurity B

Name: Closantel EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-025066

About Closantel EP Impurity B

Listed under CAS 61437-85-2, Closantel EP Impurity B is a pharmacopeial impurity of Closantel available from Vaqora Chemicals. Its molecular formula is C15H12Cl2N2 and its molecular weight is 291.2 g/mol. Systematically, it is named 2-(4-amino-2-chloro-5-methylphenyl)-2-(4-chlorophenyl)acetonitrile. Common synonyms include Closantel Sodium Dihydrate - Impurity B.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Closantel, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Closantel EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Closantel

View every impurity, metabolite and intermediate we list for Closantel.

Closantel impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Closantel EP Impurity B
Catalogue No.	VQ-025066
CAS Number	61437-85-2
IUPAC name	2-(4-amino-2-chloro-5-methylphenyl)-2-(4-chlorophenyl)acetonitrile
Molecular formula	C₁₅H₁₂Cl₂N₂
Molecular weight	291.2 g/mol
Exact mass	290.0378
Grade	Reference Standard
HSN code	38229090
InChIKey	SCNVPMWFNDBBQS-UHFFFAOYSA-N
SMILES	CC1=CC(=C(C=C1N)Cl)C(C#N)C2=CC=C(C=C2)Cl
PubChem CID	2723752

Physical properties
Physical form	Solid
LogP (XLogP3)	4.2
H-bond donors / acceptors	1 / 2
TPSA	49.8 Å²
Synonyms	Closantel Sodium Dihydrate - Impurity B, 4-Amino-2-chloro-alpha-(4-chlorophenyl)-5-methylbenzeneacetonitrile, (4-Amino-2-chloro-5-methylphenyl)(4-chlorophenyl)acetonitrile, (2RS)-(4-amino-2-chloro-5-methylphenyl)(4-chlorophenyl)ethanenitrile, 2-Amino-4-chloro-5-(4'-chlorophenyl) cyanomethyl toluene, 2-(4-amino-2-chloro-5-methyl-phenyl)-2-(4-chlorophenyl)acetonitrile, 5-chloro-4-[(4-chloro-phenyl)-cyano-methyl]-2-methylanilin, 2-(4-amino-2-chloro-5-methylphenyl)-2-(4-chlorophenyl)ethanenitrile, 4-Amino-2-chloro-.alpha.-(4-chlorophenyl)-5-methylbenzeneacetonitrile, Benzeneacetonitrile, 4-amino-2-chloro-.alpha.-(4-chlorophenyl)-5-methyl-, Benzeneacetonitrile, 4-amino-2-chloro-alpha-(4-chlorophenyl)-5-methyl-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Closantel EP Impurity B?

The CAS Registry Number of Closantel EP Impurity B is 61437-85-2. It is also known as Closantel Sodium Dihydrate - Impurity B, 4-Amino-2-chloro-alpha-(4-chlorophenyl)-5-methylbenzeneacetonitrile, (4-Amino-2-chloro-5-methylphenyl)(4-chlorophenyl)acetonitrile.

What is the molecular formula and molecular weight of Closantel EP Impurity B?

Closantel EP Impurity B has the molecular formula C15H12Cl2N2 and a molecular weight of 291.2 g/mol. Its IUPAC name is 2-(4-amino-2-chloro-5-methylphenyl)-2-(4-chlorophenyl)acetonitrile.

What is Closantel EP Impurity B used for?

Closantel EP Impurity B is supplied as a characterised reference material related to Closantel. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Closantel EP Impurity B can I order?

We supply Closantel EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Closantel EP Impurity B?

Yes. Every lot of Closantel EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Closantel EP Impurity B be shipped internationally?

Yes. Closantel EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.