Comin's reagent (2-[N,N-bis(trifluoromethyl s… 145100-51-2

Name: Comin's reagent (2-[N,N-bis(trifluoromethyl sulphonyl)amino]-5-chloropyridine), extra pure >98%
Brand: Vaqora Chemicals
SKU: VQ-020100

About Comin's reagent (2-[N,N-bis(trifluoromethyl sulphonyl)amino]-5-chloropyridine), extra pure >98%

Vaqora Chemicals supplies Comin's reagent (2-[N,N-bis(trifluoromethyl sulphonyl)amino]-5-chloropyridine) (Extra Pure grade), a pyridine derivative registered under CAS number 145100-51-2 at a purity of above 98%. With the molecular formula C7H3ClF6N2O4S2, it has a molar mass of 392.7 g/mol. The IUPAC name is N-(5-chloro-2-pyridinyl)-1,1,1-trifluoro-N-(trifluoromethylsulfonyl)methanesulfonamide. Common synonyms include N-(5-Chloro-2-pyridyl)triflimide.

Store sealed in a dry, well-ventilated location away from incompatible materials. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

It is commonly used for organic synthesis and API synthesis. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 1 g, 5 g and 25 g, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. A Safety Data Sheet (SDS) and technical specifications are available on request.

Typical applications

Organic synthesis
API synthesis

Industries

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Comin's reagent (2-[N,N-bis(trifluoromethyl sulphonyl)amino]-5-chloropyridine), extra pure >98%
Catalogue No.	VQ-020100
CAS Number	145100-51-2
IUPAC name	N-(5-chloro-2-pyridinyl)-1,1,1-trifluoro-N-(trifluoromethylsulfonyl)methanesulfonamide
Molecular formula	C₇H₃ClF₆N₂O₄S₂
Molecular weight	392.7 g/mol
Exact mass	391.9127
Grade	Extra Pure
Purity / assay	>98%
HSN code	2933
InChIKey	TUFGVZMNGTYAQD-UHFFFAOYSA-N
SMILES	C1=CC(=NC=C1Cl)N(S(=O)(=O)C(F)(F)F)S(=O)(=O)C(F)(F)F
PubChem CID	388544

Physical properties
Physical form	Other
LogP (XLogP3)	3
H-bond donors / acceptors	0 / 12
TPSA	101 Å²
Synonyms	N-(5-Chloro-2-pyridyl)triflimide, N-(5-chloropyridin-2-yl)-1,1,1-trifluoro-N-trifluoromethanesulfonylmethanesulfonamide, 2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine, 2-[N,N-Bis(trifluoromethanesulfonyl)amino]-5-chloropyridine, N-(5-Chloro-2-pyridyl)bis(trifluoromethanesulfonimide), 2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine, N-(5-chloropyridin-2-yl)-1,1,1-trifluoro-N-(trifluoromethylsulfonyl)methanesulfonamide, N-(5-chloro-2-pyridyl)-1,1,1-trifluoro-N-(trifluoromethylsulfonyl)methanesulfonamide, N-(5-chloropyridin-2-yl)-1,1,1-trifluoro-N-((trifluoromethyl)sulfonyl)methanesulfonamide, N,N-Bis(trifluoromethylsulfonyl)-5-chloro-2-pyridinamine, n-(5-chloropyridin-2-yl)-1,1,1-trifluoro-n-[(trifluoromethyl)sulfonyl]methanesulfonamide, N,N-Bis(trifluoromethylsulfonyl)-5-chloro-2-pyridylamine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Comin's reagent (2-[N,N-bis(trifluoromethyl sulphonyl)amino]-5-chloropyridine), extra pure >98%?

The CAS Registry Number of Comin's reagent (2-[N,N-bis(trifluoromethyl sulphonyl)amino]-5-chloropyridine), extra pure >98% is 145100-51-2. It is also known as N-(5-Chloro-2-pyridyl)triflimide, N-(5-chloropyridin-2-yl)-1,1,1-trifluoro-N-trifluoromethanesulfonylmethanesulfonamide, 2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine.

What is the molecular formula and molecular weight of Comin's reagent (2-[N,N-bis(trifluoromethyl sulphonyl)amino]-5-chloropyridine), extra pure >98%?

Comin's reagent (2-[N,N-bis(trifluoromethyl sulphonyl)amino]-5-chloropyridine), extra pure >98% has the molecular formula C7H3ClF6N2O4S2 and a molecular weight of 392.7 g/mol. Its IUPAC name is N-(5-chloro-2-pyridinyl)-1,1,1-trifluoro-N-(trifluoromethylsulfonyl)methanesulfonamide.

Which grade and pack sizes of Comin's reagent (2-[N,N-bis(trifluoromethyl sulphonyl)amino]-5-chloropyridine), extra pure >98% can I order?

We supply Comin's reagent (2-[N,N-bis(trifluoromethyl sulphonyl)amino]-5-chloropyridine), extra pure >98% in Extra Pure (>98%) grade, in 1 g, 5 g, 25 g packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Comin's reagent (2-[N,N-bis(trifluoromethyl sulphonyl)amino]-5-chloropyridine), extra pure >98%?

Yes. Every lot of Comin's reagent (2-[N,N-bis(trifluoromethyl sulphonyl)amino]-5-chloropyridine), extra pure >98% is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Comin's reagent (2-[N,N-bis(trifluoromethyl sulphonyl)amino]-5-chloropyridine), extra pure >98% be shipped internationally?

Yes. Comin's reagent (2-[N,N-bis(trifluoromethyl sulphonyl)amino]-5-chloropyridine), extra pure >98% is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.