Crisaborole D4

Name: Crisaborole D4
Brand: Vaqora Chemicals
SKU: VQ-047876

About Crisaborole D4

Crisaborole D4 (CAS 2268785-42-6) is a stable isotope labelled analogue related to Crisaborole offered by Vaqora Chemicals. Formula C14H10BNO3, molecular weight 255.07 g/mol. Its systematic (IUPAC) name is 2,3,5,6-tetradeuterio-4-[(1-hydroxy-3H-2,1-benzoxaborol-5-yl)oxy]benzonitrile. Common synonyms include AN-2728-d4 and TMIJ-0249.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Crisaborole and related analytes in bioanalytical, pharmacokinetic and impurity studies. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Crisaborole D4 in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Crisaborole

View every impurity, metabolite and intermediate we list for Crisaborole.

Crisaborole impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Crisaborole D4
Catalogue No.	VQ-047876
CAS Number	2268785-42-6
IUPAC name	2,3,5,6-tetradeuterio-4-[(1-hydroxy-3H-2,1-benzoxaborol-5-yl)oxy]benzonitrile
Molecular formula	C₁₄H₁₀BNO₃
Molecular weight	255.07 g/mol
Exact mass	255.1005
Grade	Reference Standard
HSN code	38229090
InChIKey	USZAGAREISWJDP-RHQRLBAQSA-N
SMILES	[2H]C1=C(C(=C(C(=C1C#N)[2H])[2H])OC2=CC3=C(B(OC3)O)C=C2)[2H]
PubChem CID	156587546

Physical properties
Physical form	Solid
H-bond donors / acceptors	1 / 4
TPSA	62.5 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Crisaborole D4?

The CAS Registry Number of Crisaborole D4 is 2268785-42-6. It is also known as 4-((1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yl)oxy)benzonitrile-2,3,5,6-d4, AN-2728-d4, TMIJ-0249.

What is the molecular formula and molecular weight of Crisaborole D4?

Crisaborole D4 has the molecular formula C14H10BNO3 and a molecular weight of 255.07 g/mol. Its IUPAC name is 2,3,5,6-tetradeuterio-4-[(1-hydroxy-3H-2,1-benzoxaborol-5-yl)oxy]benzonitrile.

What is Crisaborole D4 used for?

Crisaborole D4 is supplied as a characterised reference material related to Crisaborole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Crisaborole D4 can I order?

We supply Crisaborole D4 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Crisaborole D4?

Yes. Every lot of Crisaborole D4 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Crisaborole D4 be shipped internationally?

Yes. We export Crisaborole D4 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.