Crotamiton

Name: Crotamiton
Brand: Vaqora Chemicals
SKU: VQ-025095

About Crotamiton

Crotamiton is a high-purity reference standard of Crotamiton carrying the CAS registry number 483-63-6. With the molecular formula C13H17NO, it has a molar mass of 203.28 g/mol. The IUPAC name is N-ethyl-N-(2-methylphenyl)but-2-enamide. Common synonyms include Crotamitone and Crotalgin.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

Laboratories use this Crotamiton standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Crotamiton in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Crotamiton

View every impurity, metabolite and intermediate we list for Crotamiton.

Crotamiton impurities

Specifications & identifiers

Chemical identifiers
Product name	Crotamiton
Catalogue No.	VQ-025095
CAS Number	483-63-6
IUPAC name	N-ethyl-N-(2-methylphenyl)but-2-enamide
Molecular formula	C₁₃H₁₇NO
Molecular weight	203.28 g/mol
Exact mass	203.131
Grade	Reference Standard
HSN code	38229090
InChIKey	DNTGGZPQPQTDQF-UHFFFAOYSA-N
SMILES	CCN(C1=CC=CC=C1C)C(=O)C=CC
PubChem CID	2883

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	0 / 1
TPSA	20.3 Å²
Synonyms	Crotamitone, Crotalgin, N-ethylcrotono-o-toluidide, 2-Butenamide, N-ethyl-N-(2-methylphenyl)-, crotonyl-N-ethyl-o-toluidine, Crotamiton (Cis/Trans Mixture), Crotaglin

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation

Precautionary statements: P261, P264, P264 + P265, P270, P272, P280, P301 + P317, P302 + P352, P305 + P351 + P338, P321, P330, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Crotamiton?

The CAS Registry Number of Crotamiton is 483-63-6. It is also known as Crotamitone, Crotalgin, N-ethylcrotono-o-toluidide.

What is the molecular formula and molecular weight of Crotamiton?

Crotamiton has the molecular formula C13H17NO and a molecular weight of 203.28 g/mol. Its IUPAC name is N-ethyl-N-(2-methylphenyl)but-2-enamide.

What is Crotamiton used for?

Crotamiton is supplied as a characterised reference material related to Crotamiton. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Crotamiton can I order?

We supply Crotamiton in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Crotamiton?

Yes. Every lot of Crotamiton is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Crotamiton be shipped internationally?

Yes. Crotamiton is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.