Cyclosporin A

Name: Cyclosporin A
Brand: Vaqora Chemicals
SKU: VQ-025117

About Cyclosporin A

Cyclosporin A is a high-purity reference standard of Cyclosporine carrying the CAS registry number 59865-13-3. Formula C62H111N11O12, molecular weight 1202.6 g/mol. Common synonyms include Cyclosporin and Cyclosporine.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Cyclosporine, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Cyclosporin A in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Cyclosporine

View every impurity, metabolite and intermediate we list for Cyclosporine.

Cyclosporine impurities

Specifications & identifiers

Chemical identifiers
Product name	Cyclosporin A
Catalogue No.	VQ-025117
CAS Number	59865-13-3
IUPAC name	(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
Molecular formula	C₆₂H₁₁₁N₁₁O₁₂
Molecular weight	1202.6 g/mol
Exact mass	1201.8414
Grade	Reference Standard
HSN code	38229090
InChIKey	PMATZTZNYRCHOR-CGLBZJNRSA-N
SMILES	CC[C@H]1C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N1)[C@@H]([C@H](C)C/C=C/C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C
PubChem CID	5284373

Physical properties
Physical form	Solid
LogP (XLogP3)	7.5
H-bond donors / acceptors	5 / 12
TPSA	279 Å²
Synonyms	Cyclosporin, Cyclosporine, Ciclosporin, Neoral, Cyclosporine A, Ciclosporine, Equoral, Sang-35, Ciclosporin A, Sandimmun Neoral, Zinograf ME, S-Neoral

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H350May cause cancer
H360May damage fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P264, P270, P280, P301 + P317, P318, P319, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 59865-13-3

Cyclosporine A, ≥98.50%

CAS: 59865-13-3
Formula: C₆₂H₁₁₁N₁₁O₁₂
MW: 1202.6 g/mol

VQ-020521

Frequently asked questions

What is the CAS number of Cyclosporin A?

The CAS Registry Number of Cyclosporin A is 59865-13-3. It is also known as Cyclosporin, Cyclosporine, Ciclosporin.

What is the molecular formula and molecular weight of Cyclosporin A?

Cyclosporin A has the molecular formula C62H111N11O12 and a molecular weight of 1202.6 g/mol.

What is Cyclosporin A used for?

Cyclosporin A is supplied as a characterised reference material related to Cyclosporine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cyclosporin A can I order?

We supply Cyclosporin A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cyclosporin A?

Yes. Every lot of Cyclosporin A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cyclosporin A be shipped internationally?

Yes. Cyclosporin A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.