Defluoro Nebivolol

Name: Defluoro Nebivolol
Brand: Vaqora Chemicals
SKU: VQ-026840

About Defluoro Nebivolol

Vaqora Chemicals supplies Defluoro Nebivolol, an impurity of Nebivolol registered under CAS number 129101-34-4. The compound has the formula C22H26FNO4, corresponding to a molecular weight of 387.4 g/mol. Systematically, it is named 2-[[2-(3,4-dihydro-2H-chromen-2-yl)-2-hydroxyethyl]amino]-1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanol. Alternative names: Defluoro Nebivolol (Mixture of Diastereomers) and Desfluoro Nebivolol.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Nebivolol impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Defluoro Nebivolol in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nebivolol

View every impurity, metabolite and intermediate we list for Nebivolol.

Nebivolol impurities

Specifications & identifiers

Chemical identifiers
Product name	Defluoro Nebivolol
Catalogue No.	VQ-026840
CAS Number	129101-34-4
IUPAC name	2-[[2-(3,4-dihydro-2H-chromen-2-yl)-2-hydroxyethyl]amino]-1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanol
Molecular formula	C₂₂H₂₆FNO₄
Molecular weight	387.4 g/mol
Exact mass	387.1846
Grade	Reference Standard
HSN code	38229090
InChIKey	JMAVJQLYDMPPMQ-UHFFFAOYSA-N
SMILES	C1CC2=CC=CC=C2OC1C(CNCC(C3CCC4=C(O3)C=CC(=C4)F)O)O
PubChem CID	58409721

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	3 / 6
TPSA	71 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Defluoro Nebivolol?

The CAS Registry Number of Defluoro Nebivolol is 129101-34-4. It is also known as Defluoro Nebivolol (Mixture of Diastereomers), Desfluoro Nebivolol, 1-(chroman-2-yl)-2-((2-(6-fluorochroman-2-yl)-2-hydroxyethyl)amino)ethanol.

What is the molecular formula and molecular weight of Defluoro Nebivolol?

Defluoro Nebivolol has the molecular formula C22H26FNO4 and a molecular weight of 387.4 g/mol. Its IUPAC name is 2-[[2-(3,4-dihydro-2H-chromen-2-yl)-2-hydroxyethyl]amino]-1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanol.

What is Defluoro Nebivolol used for?

Defluoro Nebivolol is supplied as a characterised reference material related to Nebivolol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Defluoro Nebivolol can I order?

We supply Defluoro Nebivolol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Defluoro Nebivolol?

Yes. Every lot of Defluoro Nebivolol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Defluoro Nebivolol be shipped internationally?

Yes. We export Defluoro Nebivolol worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.