Dehydrosilybin

Name: Dehydrosilybin
Brand: Vaqora Chemicals
SKU: VQ-033856

About Dehydrosilybin

Dehydrosilybin (CAS 25166-14-7) is an impurity of Silibinin offered by Vaqora Chemicals. Its molecular formula is C25H20O10 and its molecular weight is 480.4 g/mol. It is also known as Dehydrosilybin A or 2,3-Dehydrosilybin.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Silibinin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Dehydrosilybin in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Silibinin

View every impurity, metabolite and intermediate we list for Silibinin.

Silibinin impurities

Specifications & identifiers

Chemical identifiers
Product name	Dehydrosilybin
Catalogue No.	VQ-033856
CAS Number	25166-14-7
IUPAC name	3,5,7-trihydroxy-2-[(2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]chromen-4-one
Molecular formula	C₂₅H₂₀O₁₀
Molecular weight	480.4 g/mol
Exact mass	480.1056
Grade	Reference Standard
HSN code	38229090
InChIKey	BVKQRAYKLBRNIK-HYBUGGRVSA-N
SMILES	COC1=C(C=CC(=C1)[C@@H]2[C@H](OC3=C(O2)C=C(C=C3)C4=C(C(=O)C5=C(C=C(C=C5O4)O)O)O)CO)O
PubChem CID	10696082

Physical properties
Physical form	Solid
LogP (XLogP3)	3.1
H-bond donors / acceptors	5 / 10
TPSA	155 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dehydrosilybin?

The CAS Registry Number of Dehydrosilybin is 25166-14-7. It is also known as Dehydrosilybin A, 2,3-Dehydrosilybin, 2,3-Dehydrosilybin A.

What is the molecular formula and molecular weight of Dehydrosilybin?

Dehydrosilybin has the molecular formula C25H20O10 and a molecular weight of 480.4 g/mol. Its IUPAC name is 3,5,7-trihydroxy-2-[(2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]chromen-4-one.

What is Dehydrosilybin used for?

Dehydrosilybin is supplied as a characterised reference material related to Silibinin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dehydrosilybin can I order?

We supply Dehydrosilybin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dehydrosilybin?

Yes. Every lot of Dehydrosilybin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dehydrosilybin be shipped internationally?

Yes. Dehydrosilybin is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.