Silybin B

Name: Silybin B
Brand: Vaqora Chemicals
SKU: VQ-033855

About Silybin B

Listed under CAS 142797-34-0, Silybin B is an impurity of Silybin available from Vaqora Chemicals. Formula C25H22O10, molecular weight 482.4 g/mol. Alternative names: Silibinin B and SILYBIN (A and B)(P).

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This Silybin impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Silybin B in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Silybin

View every impurity, metabolite and intermediate we list for Silybin.

Silybin impurities

Specifications & identifiers

Chemical identifiers
Product name	Silybin B
Catalogue No.	VQ-033855
CAS Number	142797-34-0
IUPAC name	(2R,3R)-3,5,7-trihydroxy-2-[(2S,3S)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydrochromen-4-one
Molecular formula	C₂₅H₂₂O₁₀
Molecular weight	482.4 g/mol
Exact mass	482.1213
Grade	Reference Standard
HSN code	38229090
InChIKey	SEBFKMXJBCUCAI-WAABAYLZSA-N
SMILES	COC1=C(C=CC(=C1)[C@H]2[C@@H](OC3=C(O2)C=C(C=C3)[C@@H]4[C@H](C(=O)C5=C(C=C(C=C5O4)O)O)O)CO)O
PubChem CID	1548994

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	5 / 10
TPSA	155 Å²
Synonyms	Silibinin B, SILYBIN (A and B)(P), Legalon 70, Silymarin B, Silybin A and B, Milk thistle [NF]

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Silybin B?

The CAS Registry Number of Silybin B is 142797-34-0. It is also known as Silibinin B, SILYBIN (A and B)(P), Legalon 70.

What is the molecular formula and molecular weight of Silybin B?

Silybin B has the molecular formula C25H22O10 and a molecular weight of 482.4 g/mol. Its IUPAC name is (2R,3R)-3,5,7-trihydroxy-2-[(2S,3S)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydrochromen-4-one.

What is Silybin B used for?

Silybin B is supplied as a characterised reference material related to Silybin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Silybin B can I order?

We supply Silybin B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Silybin B?

Yes. Every lot of Silybin B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Silybin B be shipped internationally?

Yes. Silybin B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.