Dexamethasone EP Impurity E

Name: Dexamethasone EP Impurity E
Brand: Vaqora Chemicals
SKU: VQ-006321

About Dexamethasone EP Impurity E

Listed under CAS 13209-41-1, Dexamethasone EP Impurity E is a pharmacopeial impurity of Dexamethasone available from Vaqora Chemicals. Formula C22H28O4, molecular weight 356.5 g/mol. It is also known as VBP 15 or Vamorolone.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Dexamethasone, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Dexamethasone EP Impurity E in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Dexamethasone

View every impurity, metabolite and intermediate we list for Dexamethasone.

Dexamethasone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Dexamethasone EP Impurity E
Catalogue No.	VQ-006321
CAS Number	13209-41-1
IUPAC name	(8S,10S,13S,14S,16R,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-3-one
Molecular formula	C₂₂H₂₈O₄
Molecular weight	356.5 g/mol
Exact mass	356.1988
Grade	Reference Standard
HSN code	38229090
InChIKey	ZYTXTXAMMDTYDQ-DGEXFFLYSA-N
SMILES	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4(C3=CC[C@@]2([C@]1(C(=O)CO)O)C)C
PubChem CID	3035000

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	2 / 4
TPSA	74.6 Å²
Synonyms	(16α)-17,21-Dihydroxy-16-methylpregna-1,4,9(11)-triene-3,20-dione, 17,21-Dihydroxy-16alpha-methylpregna-1,4,9(11)-triene-3,20-dione, 17alpha ,21-Dihydroxy-16alpha-methylpregna-1,4,9(11)-triene-3,20-dione, VBP 15, Vamorolone, VBP-15 free alcohol, VBP-15, 9,11-dehydro dexamethasone, (16alpha)-17,21-dihydroxy-16-methylpregna-1,4,9(11)-triene-3,20-dione, VBP15, 16a-Methyl-9,11-dehydro Prednisolone, Agamree (TN)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H319Causes serious eye irritation

Precautionary statements: P261, P264, P264 + P265, P270, P272, P280, P301 + P317, P302 + P352, P305 + P351 + P338, P321, P330, P333 + P317, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dexamethasone EP Impurity E?

The CAS Registry Number of Dexamethasone EP Impurity E is 13209-41-1. It is also known as (16α)-17,21-Dihydroxy-16-methylpregna-1,4,9(11)-triene-3,20-dione, 17,21-Dihydroxy-16alpha-methylpregna-1,4,9(11)-triene-3,20-dione, 17alpha ,21-Dihydroxy-16alpha-methylpregna-1,4,9(11)-triene-3,20-dione.

What is the molecular formula and molecular weight of Dexamethasone EP Impurity E?

Dexamethasone EP Impurity E has the molecular formula C22H28O4 and a molecular weight of 356.5 g/mol. Its IUPAC name is (8S,10S,13S,14S,16R,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-3-one.

What is Dexamethasone EP Impurity E used for?

Dexamethasone EP Impurity E is supplied as a characterised reference material related to Dexamethasone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dexamethasone EP Impurity E can I order?

We supply Dexamethasone EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dexamethasone EP Impurity E?

Yes. Every lot of Dexamethasone EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dexamethasone EP Impurity E be shipped internationally?

Yes. Dexamethasone EP Impurity E is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.