Dexamethasone Oxetanone

Name: Dexamethasone Oxetanone
Brand: Vaqora Chemicals
SKU: VQ-013357

About Dexamethasone Oxetanone

Dexamethasone Oxetanone is a process intermediate or related compound of Dexamethasone carrying the CAS registry number 4089-36-5. Formula C22H27FO4, molecular weight 374.4 g/mol.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

It is a process intermediate or related compound in the synthesis of Dexamethasone, useful for route development, impurity fate-and-purge studies and analytical method development. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Dexamethasone Oxetanone in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Dexamethasone

View every impurity, metabolite and intermediate we list for Dexamethasone.

Dexamethasone impurities

Specifications & identifiers

Chemical identifiers
Product name	Dexamethasone Oxetanone
Catalogue No.	VQ-013357
CAS Number	4089-36-5
IUPAC name	(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11-hydroxy-10,13,16-trimethylspiro[6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17,2'-oxetane]-3,3'-dione
Molecular formula	C₂₂H₂₇FO₄
Molecular weight	374.4 g/mol
Exact mass	374.1893
Grade	Reference Standard
InChIKey	PLIOZIVVVLFDAA-CXSFZGCWSA-N
SMILES	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@@]15C(=O)CO5)C)O)F)C
PubChem CID	9885914

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	1 / 5
TPSA	63.6 Å²
Synonyms	17,21-Epoxy-9-fluoro-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione, (11β,16α)-17,21-Epoxy-9-fluoro-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione, Pregna-1,4-diene-3,20-dione, 17,21-epoxy-9-fluoro-11-hydroxy-16-methyl-, (11beta,16alpha)-, (11beta,16alpha)-17,21-Epoxy-9-fluoro-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione, Pregna-1,4-diene-3,20-dione, 17,21-epoxy-9-fluoro-11beta-hydroxy-16alpha-methyl-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dexamethasone Oxetanone?

The CAS Registry Number of Dexamethasone Oxetanone is 4089-36-5. It is also known as 17,21-Epoxy-9-fluoro-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione, (11β,16α)-17,21-Epoxy-9-fluoro-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione, Pregna-1,4-diene-3,20-dione, 17,21-epoxy-9-fluoro-11-hydroxy-16-methyl-, (11beta,16alpha)-.

What is the molecular formula and molecular weight of Dexamethasone Oxetanone?

Dexamethasone Oxetanone has the molecular formula C22H27FO4 and a molecular weight of 374.4 g/mol. Its IUPAC name is (8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11-hydroxy-10,13,16-trimethylspiro[6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17,2'-oxetane]-3,3'-dione.

What is Dexamethasone Oxetanone used for?

Dexamethasone Oxetanone is supplied as a characterised reference material related to Dexamethasone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dexamethasone Oxetanone can I order?

We supply Dexamethasone Oxetanone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dexamethasone Oxetanone?

Yes. Every lot of Dexamethasone Oxetanone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dexamethasone Oxetanone be shipped internationally?

Yes. We export Dexamethasone Oxetanone worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.