Diclofenac EP Impurity E

Name: Diclofenac EP Impurity E
Brand: Vaqora Chemicals
SKU: VQ-022369

About Diclofenac EP Impurity E

Diclofenac EP Impurity E is a pharmacopeial impurity of Diclofenac carrying the CAS registry number 59-48-3. With the molecular formula C8H7NO, it has a molar mass of 133.15 g/mol. Systematically, it is named 1,3-dihydroindol-2-one. Alternative names: Oxindole and Diclofenac Sodium - Impurity E.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Diclofenac to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Diclofenac

View every impurity, metabolite and intermediate we list for Diclofenac.

Diclofenac impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Diclofenac EP Impurity E
Catalogue No.	VQ-022369
CAS Number	59-48-3
IUPAC name	1,3-dihydroindol-2-one
Molecular formula	C₈H₇NO
Molecular weight	133.15 g/mol
Exact mass	133.0528
Grade	Reference Standard
HSN code	38229090
InChIKey	JYGFTBXVXVMTGB-UHFFFAOYSA-N
SMILES	C1C2=CC=CC=C2NC1=O
PubChem CID	321710

Physical properties
Physical form	Solid
LogP (XLogP3)	1.2
H-bond donors / acceptors	1 / 1
TPSA	29.1 Å²
Synonyms	Oxindole, Diclofenac Sodium - Impurity E, 2-Oxindole, 2-Indolinone, 1,3-Dihydro-2H-indol-2-one, Oxindol, Indol-2(3H)-one, 2H-Indol-2-one, 1,3-dihydro-, Indoline-2-one, indol-2-ol, 2-hydroxyindole, Indolin-2-one

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 59-48-3

Extra Pure

Oxindole, extra pure >97%

CAS: 59-48-3
Formula: C₈H₇NO
MW: 133.15 g/mol

VQ-019921

Frequently asked questions

What is the CAS number of Diclofenac EP Impurity E?

The CAS Registry Number of Diclofenac EP Impurity E is 59-48-3. It is also known as Oxindole, Diclofenac Sodium - Impurity E, 2-Oxindole.

What is the molecular formula and molecular weight of Diclofenac EP Impurity E?

Diclofenac EP Impurity E has the molecular formula C8H7NO and a molecular weight of 133.15 g/mol. Its IUPAC name is 1,3-dihydroindol-2-one.

What is Diclofenac EP Impurity E used for?

Diclofenac EP Impurity E is supplied as a characterised reference material related to Diclofenac. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Diclofenac EP Impurity E can I order?

We supply Diclofenac EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Diclofenac EP Impurity E?

Yes. Every lot of Diclofenac EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Diclofenac EP Impurity E be shipped internationally?

Yes. Diclofenac EP Impurity E is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.