Diphenhydramine EP Impurity B

Name: Diphenhydramine EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-025328

About Diphenhydramine EP Impurity B

Diphenhydramine EP Impurity B (CAS 19804-27-4) is a pharmacopeial impurity of Orphenadrine offered by Vaqora Chemicals. Its molecular formula is C18H23NO and its molecular weight is 269.4 g/mol. Systematically, it is named N,N-dimethyl-2-[(4-methylphenyl)-phenylmethoxy]ethanamine. Common synonyms include Toladryl and Diphenhydramine - Impurity B.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Orphenadrine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Orphenadrine

View every impurity, metabolite and intermediate we list for Orphenadrine.

Orphenadrine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Diphenhydramine EP Impurity B
Catalogue No.	VQ-025328
CAS Number	19804-27-4
IUPAC name	N,N-dimethyl-2-[(4-methylphenyl)-phenylmethoxy]ethanamine
Molecular formula	C₁₈H₂₃NO
Molecular weight	269.4 g/mol
Exact mass	269.178
Grade	Reference Standard
HSN code	38229090
InChIKey	PJUYQWIDNIAHIZ-UHFFFAOYSA-N
SMILES	CC1=CC=C(C=C1)C(C2=CC=CC=C2)OCCN(C)C
PubChem CID	19935

Physical properties
Physical form	Solid
LogP (XLogP3)	3.6
H-bond donors / acceptors	0 / 2
TPSA	12.5 Å²
Synonyms	Toladryl, Diphenhydramine - Impurity B, Dimenhydrinate EP Impurity G, Orphenadrine EP Impurity F, 4-Methyldiphenhydramine, p-Methyldiphenhydramine, N,N-Dimethyl-2-[(4-methylphenyl)phenylmethoxy]ethanamine, Neo-benodine, Diphenhydramine Impurity B, p-Methylbenzhydryl 2-Dimethylaminoethyl Ether, Ethanamine, 2-[(4-methylphenyl)(phenyl)methoxy]-N,N-dimethyl-, N,N-Dimethyl-2-((4-methylphenyl)phenylmethoxy)ethanamine

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Diphenhydramine EP Impurity B?

The CAS Registry Number of Diphenhydramine EP Impurity B is 19804-27-4. It is also known as Toladryl, Diphenhydramine - Impurity B, Dimenhydrinate EP Impurity G.

What is the molecular formula and molecular weight of Diphenhydramine EP Impurity B?

Diphenhydramine EP Impurity B has the molecular formula C18H23NO and a molecular weight of 269.4 g/mol. Its IUPAC name is N,N-dimethyl-2-[(4-methylphenyl)-phenylmethoxy]ethanamine.

What is Diphenhydramine EP Impurity B used for?

Diphenhydramine EP Impurity B is supplied as a characterised reference material related to Orphenadrine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Diphenhydramine EP Impurity B can I order?

We supply Diphenhydramine EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Diphenhydramine EP Impurity B?

Yes. Every lot of Diphenhydramine EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Diphenhydramine EP Impurity B be shipped internationally?

Yes. We export Diphenhydramine EP Impurity B worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.