Donepezil-4-hydroxy

Name: Donepezil-4-hydroxy
Brand: Vaqora Chemicals
SKU: VQ-030277

About Donepezil-4-hydroxy

Donepezil-4-hydroxy is a metabolite or degradation product of Donepezil carrying the CAS registry number 197010-22-3. With the molecular formula C24H29NO4, it has a molar mass of 395.5 g/mol. Its systematic (IUPAC) name is 2-[(1-benzyl-4-hydroxypiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Donepezil, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Donepezil-4-hydroxy in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Donepezil

View every impurity, metabolite and intermediate we list for Donepezil.

Donepezil impurities

Specifications & identifiers

Chemical identifiers
Product name	Donepezil-4-hydroxy
Catalogue No.	VQ-030277
CAS Number	197010-22-3
IUPAC name	2-[(1-benzyl-4-hydroxypiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one
Molecular formula	C₂₄H₂₉NO₄
Molecular weight	395.5 g/mol
Exact mass	395.2097
Grade	Reference Standard
HSN code	38229090
InChIKey	JTNHBPVFDCDXDA-UHFFFAOYSA-N
SMILES	COC1=C(C=C2C(=C1)CC(C2=O)CC3(CCN(CC3)CC4=CC=CC=C4)O)OC
PubChem CID	137346599

Physical properties
Physical form	Solid
LogP (XLogP3)	3.2
H-bond donors / acceptors	1 / 5
TPSA	59 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Donepezil-4-hydroxy?

The CAS Registry Number of Donepezil-4-hydroxy is 197010-22-3. It is also known as 2-((1-Benzyl-4-hydroxypiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one.

What is the molecular formula and molecular weight of Donepezil-4-hydroxy?

Donepezil-4-hydroxy has the molecular formula C24H29NO4 and a molecular weight of 395.5 g/mol. Its IUPAC name is 2-[(1-benzyl-4-hydroxypiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one.

What is Donepezil-4-hydroxy used for?

Donepezil-4-hydroxy is supplied as a characterised reference material related to Donepezil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Donepezil-4-hydroxy can I order?

We supply Donepezil-4-hydroxy in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Donepezil-4-hydroxy?

Yes. Every lot of Donepezil-4-hydroxy is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Donepezil-4-hydroxy be shipped internationally?

Yes. We export Donepezil-4-hydroxy worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.