Donepezil Hydrochloride

Name: Donepezil Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-007433

About Donepezil Hydrochloride

Listed under CAS 120011-70-3, Donepezil Hydrochloride is a high-purity reference standard of Donepezil available from Vaqora Chemicals. Its molecular formula is C24H30ClNO3 and its molecular weight is 416.0 g/mol. Systematically, it is named 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one. Hydrochloride. Alternative names: Aricept and Aricept D.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 3 hazard statements. Review the Safety Data Sheet before use.

Laboratories use this Donepezil standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Donepezil Hydrochloride is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Donepezil

View every impurity, metabolite and intermediate we list for Donepezil.

Donepezil impurities

Specifications & identifiers

Chemical identifiers
Product name	Donepezil Hydrochloride
Catalogue No.	VQ-007433
CAS Number	120011-70-3
Other CAS	120014-06-4
IUPAC name	2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one;hydrochloride
Molecular formula	C₂₄H₃₀ClNO₃
Molecular weight	416 g/mol
Exact mass	415.1914
Grade	Reference Standard
HSN code	38229090
InChIKey	XWAIAVWHZJNZQQ-UHFFFAOYSA-N
SMILES	COC1=C(C=C2C(=C1)CC(C2=O)CC3CCN(CC3)CC4=CC=CC=C4)OC.Cl
PubChem CID	5741

Physical properties
Physical form	Solid
H-bond donors / acceptors	1 / 4
TPSA	38.8 Å²
Synonyms	2-(1-Benzyl-4-piperidylmethyl)-5,6-dimethoxy-1-indanone Hydrochloride, 1-Benzyl-4-[(5,6-dimethoxy-1-indanon-2-yl)methyl]piperidine hydrochloride, Aricept, Aricept D, Aricept ODT, BNAG, Donep, Dopezil, Dorent, Donepezil HCl, Aricept Evess, 1-Benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine hcl

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H300Fatal if swallowed
H301Toxic if swallowed
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P270, P280, P301 + P316, P305 + P351 + P338, P321, P330, P337 + P317, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 120011-70-3

Donepezil hydrochloride, ≥98%

CAS: 120011-70-3
Formula: C₂₄H₃₀ClNO₃
MW: 416 g/mol

VQ-012506

Frequently asked questions

What is the CAS number of Donepezil Hydrochloride?

The CAS Registry Number of Donepezil Hydrochloride is 120011-70-3. It is also known as 2-(1-Benzyl-4-piperidylmethyl)-5,6-dimethoxy-1-indanone Hydrochloride, 1-Benzyl-4-[(5,6-dimethoxy-1-indanon-2-yl)methyl]piperidine hydrochloride, Aricept.

What is the molecular formula and molecular weight of Donepezil Hydrochloride?

Donepezil Hydrochloride has the molecular formula C24H30ClNO3 and a molecular weight of 416 g/mol.

What is Donepezil Hydrochloride used for?

Donepezil Hydrochloride is supplied as a characterised reference material related to Donepezil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Donepezil Hydrochloride can I order?

We supply Donepezil Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Donepezil Hydrochloride?

Yes. Every lot of Donepezil Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Donepezil Hydrochloride be shipped internationally?

Yes. Donepezil Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.