Dorzolamide Impurity B

Name: Dorzolamide Impurity B
Brand: Vaqora Chemicals
SKU: VQ-022435

About Dorzolamide Impurity B

Listed under CAS 149249-72-9, Dorzolamide Impurity B is an impurity of Dorzolamide available from Vaqora Chemicals. Formula C10H16N2O4S3, molecular weight 324.4 g/mol. Its systematic (IUPAC) name is (4R,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide. Common synonyms include (4R)-Dorzolamide and (4R, 6S)-Dorzolamide EP Impurity B.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Dorzolamide to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Dorzolamide

View every impurity, metabolite and intermediate we list for Dorzolamide.

Dorzolamide impurities

Specifications & identifiers

Chemical identifiers
Product name	Dorzolamide Impurity B
Catalogue No.	VQ-022435
CAS Number	149249-72-9
IUPAC name	(4R,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide
Molecular formula	C₁₀H₁₆N₂O₄S₃
Molecular weight	324.4 g/mol
Exact mass	324.0272
Grade	Reference Standard
HSN code	38229090
InChIKey	IAVUPMFITXYVAF-POYBYMJQSA-N
SMILES	CCN[C@@H]1C[C@@H](S(=O)(=O)C2=C1C=C(S2)S(=O)(=O)N)C
PubChem CID	6604453

Physical properties
Physical form	Solid
LogP (XLogP3)	0.4
H-bond donors / acceptors	2 / 7
TPSA	151 Å²
Synonyms	(4R)-Dorzolamide, (4R, 6S)-Dorzolamide EP Impurity B, Dorzolamide, (+/-)-(cis)-, (+/-)-(cis)-dorzolamide, (+/-)-(Cis)-4R,6R-dorzolamide, rac-cis-Dorzolamide

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dorzolamide Impurity B?

The CAS Registry Number of Dorzolamide Impurity B is 149249-72-9. It is also known as (4R)-Dorzolamide, (4R, 6S)-Dorzolamide EP Impurity B, Dorzolamide, (+/-)-(cis)-.

What is the molecular formula and molecular weight of Dorzolamide Impurity B?

Dorzolamide Impurity B has the molecular formula C10H16N2O4S3 and a molecular weight of 324.4 g/mol. Its IUPAC name is (4R,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide.

What is Dorzolamide Impurity B used for?

Dorzolamide Impurity B is supplied as a characterised reference material related to Dorzolamide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dorzolamide Impurity B can I order?

We supply Dorzolamide Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dorzolamide Impurity B?

Yes. Every lot of Dorzolamide Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dorzolamide Impurity B be shipped internationally?

Yes. Dorzolamide Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.