Dorzolamide EP Impurity A

Name: Dorzolamide EP Impurity A
Brand: Vaqora Chemicals
SKU: VQ-025379

About Dorzolamide EP Impurity A

Listed under CAS 120279-95-0, Dorzolamide EP Impurity A is a pharmacopeial impurity of Dorzolamide available from Vaqora Chemicals. The compound has the formula C10H16N2O4S3, corresponding to a molecular weight of 324.4 g/mol. Its systematic (IUPAC) name is (4R,6R)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide. Common synonyms include ent-Dorzolamide and Dorzolamide - Impurity A.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

This Dorzolamide impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Dorzolamide EP Impurity A is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Dorzolamide

View every impurity, metabolite and intermediate we list for Dorzolamide.

Dorzolamide impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Dorzolamide EP Impurity A
Catalogue No.	VQ-025379
CAS Number	120279-95-0
IUPAC name	(4R,6R)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide
Molecular formula	C₁₀H₁₆N₂O₄S₃
Molecular weight	324.4 g/mol
Exact mass	324.0272
Grade	Reference Standard
HSN code	38229090
InChIKey	IAVUPMFITXYVAF-HTRCEHHLSA-N
SMILES	CCN[C@@H]1C[C@H](S(=O)(=O)C2=C1C=C(S2)S(=O)(=O)N)C
PubChem CID	92087

Physical properties
Physical form	Solid
LogP (XLogP3)	0.4
H-bond donors / acceptors	2 / 7
TPSA	151 Å²
Synonyms	ent-Dorzolamide, Dorzolamide - Impurity A, (+)-(Trans)-dorzolamide, Dorzolamide impurity A, Dorzolamide, 4R,6R-, (+)-4R,6R-Dorzolamide, (4R,6R)-Dorzolamide, Dorzolamide, (+)-(trans)-, sulfonamide 5, Dorzolamide, DZA

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H362May cause harm to breast-fed children
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P263, P264, P270, P301 + P317, P318, P319, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dorzolamide EP Impurity A?

The CAS Registry Number of Dorzolamide EP Impurity A is 120279-95-0. It is also known as ent-Dorzolamide, Dorzolamide - Impurity A, (+)-(Trans)-dorzolamide.

What is the molecular formula and molecular weight of Dorzolamide EP Impurity A?

Dorzolamide EP Impurity A has the molecular formula C10H16N2O4S3 and a molecular weight of 324.4 g/mol. Its IUPAC name is (4R,6R)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide.

What is Dorzolamide EP Impurity A used for?

Dorzolamide EP Impurity A is supplied as a characterised reference material related to Dorzolamide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dorzolamide EP Impurity A can I order?

We supply Dorzolamide EP Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dorzolamide EP Impurity A?

Yes. Every lot of Dorzolamide EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dorzolamide EP Impurity A be shipped internationally?

Yes. Dorzolamide EP Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.