Duloxetine Hydrochloride

Name: Duloxetine Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-007442

About Duloxetine Hydrochloride

Listed under CAS 136434-34-9, Duloxetine Hydrochloride is a high-purity reference standard of Duloxetine available from Vaqora Chemicals. Its molecular formula is C18H20ClNOS and its molecular weight is 333.9 g/mol. Its systematic (IUPAC) name is (3S)-N-methyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine. Hydrochloride. Common synonyms include (S)-Duloxetine hydrochloride and Cymbalta.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this Duloxetine standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Duloxetine Hydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Duloxetine

View every impurity, metabolite and intermediate we list for Duloxetine.

Duloxetine impurities

Specifications & identifiers

Chemical identifiers
Product name	Duloxetine Hydrochloride
Catalogue No.	VQ-007442
CAS Number	136434-34-9
Other CAS	116539-59-4
IUPAC name	(3S)-N-methyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine;hydrochloride
Molecular formula	C₁₈H₂₀ClNOS
Molecular weight	333.9 g/mol
Exact mass	333.0954
Grade	Reference Standard
HSN code	38229090
InChIKey	BFFSMCNJSOPUAY-LMOVPXPDSA-N
SMILES	CNCC[C@@H](C1=CC=CS1)OC2=CC=CC3=CC=CC=C32.Cl
PubChem CID	60834

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 3
TPSA	49.5 Å²
Synonyms	(+)-N-Methyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine hydrochloride, (S)-Duloxetine hydrochloride, (S)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine hydrochloride, Cymbalta, Drizalma Sprinkle, Dulane 20, Irenka, Yentreve, Duloxetine HCl, Duloxetine mylan, Duloxetine (as hydrochloride), Duloxetine Boehringer Ingelheim

Safety & hazard information (GHS)

Corrosive

Toxic

Harmful / irritant

Environmental hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H302Harmful if swallowed
H318Causes serious eye damage
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P264, P264 + P265, P270, P273, P280, P301 + P316, P301 + P317, P305 + P354 + P338, P317, P321, P330, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Duloxetine Hydrochloride?

The CAS Registry Number of Duloxetine Hydrochloride is 136434-34-9. It is also known as (+)-N-Methyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine hydrochloride, (S)-Duloxetine hydrochloride, (S)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine hydrochloride.

What is the molecular formula and molecular weight of Duloxetine Hydrochloride?

Duloxetine Hydrochloride has the molecular formula C18H20ClNOS and a molecular weight of 333.9 g/mol.

What is Duloxetine Hydrochloride used for?

Duloxetine Hydrochloride is supplied as a characterised reference material related to Duloxetine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Duloxetine Hydrochloride can I order?

We supply Duloxetine Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Duloxetine Hydrochloride?

Yes. Every lot of Duloxetine Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Duloxetine Hydrochloride be shipped internationally?

Yes. Duloxetine Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.