(E)-3-(4-Amino-3,5-dimethylphenyl)acrylonitri… 661489-23-2

Name: (E)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-027818

About (E)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile Hydrochloride

Listed under CAS 661489-23-2, (E)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile Hydrochloride is an impurity of Rilpivirine available from Vaqora Chemicals. The compound has the formula C11H13ClN2, corresponding to a molecular weight of 208.69 g/mol.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 7 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Rilpivirine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer (E)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile Hydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Rilpivirine

View every impurity, metabolite and intermediate we list for Rilpivirine.

Rilpivirine impurities

Specifications & identifiers

Chemical identifiers
Product name	(E)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile Hydrochloride
Catalogue No.	VQ-027818
CAS Number	661489-23-2
IUPAC name	(E)-3-(4-amino-3,5-dimethylphenyl)prop-2-enenitrile;hydrochloride
Molecular formula	C₁₁H₁₃ClN₂
Molecular weight	208.69 g/mol
Exact mass	208.0767
Grade	Reference Standard
HSN code	38229090
InChIKey	DHBOHGCHPDMVOD-BJILWQEISA-N
SMILES	CC1=CC(=CC(=C1N)C)/C=C/C#N.Cl
PubChem CID	68291229

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 2
TPSA	49.8 Å²
Synonyms	(E)-3-(4-Amino-3,5-dimethylphenyl)-2-propenenitrile Hydrochloride, (2E)-3-(4-amino-3,5-dimethylphenyl)prop-2-enenitrile hydrochloride, (2E)-3-(4-Amino-3,5-dimethylphenyl)-2-propenenitrile Hydrochloride, 2-Propenenitrile, 3-(4-amino-3,5-dimethylphenyl)-, hydrochloride (1:1), (2E)-, 3-(4-Amino-3,5-dimethylphenyl)acrylonitrile hydrochloride, (E)-, (2E)-3-(4-Amino-3,5-dimethylphenyl)prop-2-enenitrile--hydrogen chloride (1/1), 2-Propenenitrile, 3-(4-amino-3,5-dimethylphenyl)-, monohydrochloride, (2E)-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302+H312+H332Harmful if swallowed, in contact with skin or if inhaled
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (E)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile Hydrochloride?

The CAS Registry Number of (E)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile Hydrochloride is 661489-23-2. It is also known as (E)-3-(4-Amino-3,5-dimethylphenyl)-2-propenenitrile Hydrochloride, (2E)-3-(4-amino-3,5-dimethylphenyl)prop-2-enenitrile hydrochloride, (2E)-3-(4-Amino-3,5-dimethylphenyl)-2-propenenitrile Hydrochloride.

What is the molecular formula and molecular weight of (E)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile Hydrochloride?

(E)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile Hydrochloride has the molecular formula C11H13ClN2 and a molecular weight of 208.69 g/mol.

What is (E)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile Hydrochloride used for?

(E)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile Hydrochloride is supplied as a characterised reference material related to Rilpivirine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (E)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile Hydrochloride can I order?

We supply (E)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (E)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile Hydrochloride?

Yes. Every lot of (E)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (E)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile Hydrochloride be shipped internationally?

Yes. (E)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.