(Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitri… 661489-22-1

Name: (Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile
Brand: Vaqora Chemicals
SKU: VQ-033542

About (Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile

Listed under CAS 661489-22-1, (Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile is an impurity of Rilpivirine available from Vaqora Chemicals. Formula C11H12N2, molecular weight 172.23 g/mol. The IUPAC name is (Z)-3-(4-amino-3,5-dimethylphenyl)prop-2-enenitrile. It is also known as Rilpivirine Nitrile Z-isomer.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Rilpivirine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer (Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Rilpivirine

View every impurity, metabolite and intermediate we list for Rilpivirine.

Rilpivirine impurities

Specifications & identifiers

Chemical identifiers
Product name	(Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile
Catalogue No.	VQ-033542
CAS Number	661489-22-1
IUPAC name	(Z)-3-(4-amino-3,5-dimethylphenyl)prop-2-enenitrile
Molecular formula	C₁₁H₁₂N₂
Molecular weight	172.23 g/mol
Exact mass	172.1
Grade	Reference Standard
HSN code	38229090
InChIKey	JNRBSZUSHVFWIK-ARJAWSKDSA-N
SMILES	CC1=CC(=CC(=C1N)C)/C=C\C#N
PubChem CID	71313211

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	1 / 2
TPSA	49.8 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile?

The CAS Registry Number of (Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile is 661489-22-1. It is also known as Rilpivirine Nitrile Z-isomer, (2Z)-3-(4-Amino-3,5-dimethylphenyl)-2-propenenitrile, 3-(4-Amino-3,5-dimethylphenyl)acrylonitrile, (Z)-.

What is the molecular formula and molecular weight of (Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile?

(Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile has the molecular formula C11H12N2 and a molecular weight of 172.23 g/mol. Its IUPAC name is (Z)-3-(4-amino-3,5-dimethylphenyl)prop-2-enenitrile.

What is (Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile used for?

(Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile is supplied as a characterised reference material related to Rilpivirine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile can I order?

We supply (Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile?

Yes. Every lot of (Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile be shipped internationally?

Yes. We export (Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.