Entacapone EP Impurity B

Name: Entacapone EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-030486

About Entacapone EP Impurity B

Entacapone EP Impurity B is a pharmacopeial impurity of Entacapone carrying the CAS registry number 1215039-66-9. With the molecular formula C12H10N2O6, it has a molar mass of 278.22 g/mol. Its systematic (IUPAC) name is ethyl (E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)prop-2-enoate. Alternative names: Entacapone - Impurity B and OR 545.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Entacapone impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Entacapone EP Impurity B is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Entacapone

View every impurity, metabolite and intermediate we list for Entacapone.

Entacapone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Entacapone EP Impurity B
Catalogue No.	VQ-030486
CAS Number	1215039-66-9
IUPAC name	ethyl (E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)prop-2-enoate
Molecular formula	C₁₂H₁₀N₂O₆
Molecular weight	278.22 g/mol
Exact mass	278.0539
Grade	Reference Standard
HSN code	38229090
InChIKey	KZGBADQGBKGUGS-FPYGCLRLSA-N
SMILES	CCOC(=O)/C(=C/C1=CC(=C(C(=C1)O)O)[N+](=O)[O-])/C#N
PubChem CID	44380432

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	2 / 7
TPSA	136 Å²
Synonyms	Entacapone - Impurity B, Ethyl (2E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)prop-2-enoate, OR 545, Ethyl (E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)acrylate, OR-545, 2-Propenoic acid, 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-, ethyl ester, Ethyl(2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)prop-2-enoate, (E)-Ethyl 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)acrylate, 2-Cyano-3-(3,4-dihydroxy-5-nitro-phenyl)-acrylic acid ethyl ester, ethyl (E)-2-cyano-3-(3,4-dihydroxy-5-nitro-phenyl)prop-2-enoate

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Entacapone EP Impurity B?

The CAS Registry Number of Entacapone EP Impurity B is 1215039-66-9. It is also known as Entacapone - Impurity B, Ethyl (2E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)prop-2-enoate, OR 545.

What is the molecular formula and molecular weight of Entacapone EP Impurity B?

Entacapone EP Impurity B has the molecular formula C12H10N2O6 and a molecular weight of 278.22 g/mol. Its IUPAC name is ethyl (E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)prop-2-enoate.

What is Entacapone EP Impurity B used for?

Entacapone EP Impurity B is supplied as a characterised reference material related to Entacapone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Entacapone EP Impurity B can I order?

We supply Entacapone EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Entacapone EP Impurity B?

Yes. Every lot of Entacapone EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Entacapone EP Impurity B be shipped internationally?

Yes. We export Entacapone EP Impurity B worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.