Entecavir EP Impurity D

Name: Entecavir EP Impurity D
Brand: Vaqora Chemicals
SKU: VQ-022537

About Entecavir EP Impurity D

Entecavir EP Impurity D is a pharmacopeial impurity of Entecavir carrying the CAS registry number 1367369-80-9. With the molecular formula C12H15N5O3, it has a molar mass of 277.28 g/mol. Its systematic (IUPAC) name is 2-amino-9-[(1S,3R,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-1H-purin-6-one. Alternative names: 4-epi-Entecavir and Entecavir USP Impurity D.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Entecavir to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Entecavir EP Impurity D in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Entecavir

View every impurity, metabolite and intermediate we list for Entecavir.

Entecavir impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Entecavir EP Impurity D
Catalogue No.	VQ-022537
CAS Number	1367369-80-9
IUPAC name	2-amino-9-[(1S,3R,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-1H-purin-6-one
Molecular formula	C₁₂H₁₅N₅O₃
Molecular weight	277.28 g/mol
Exact mass	277.1175
Grade	Reference Standard
HSN code	38229090
InChIKey	QDGZDCVAUDNJFG-BIIVOSGPSA-N
SMILES	C=C1[C@H](C[C@H]([C@H]1CO)O)N2C=NC3=C2N=C(NC3=O)N
PubChem CID	135908333

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.3
H-bond donors / acceptors	4 / 5
TPSA	126 Å²
Synonyms	4-epi-Entecavir, Entecavir USP Impurity D, Entecavir Monohydrate - Impurity D, Entecavir 4-epimer, 9-((1S,3R,4R)-4-Hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)guanine, 4'-epi-Entecavir, (1'S,3'S,4'S)-Entecavir IsoMer

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Entecavir EP Impurity D?

The CAS Registry Number of Entecavir EP Impurity D is 1367369-80-9. It is also known as 4-epi-Entecavir, Entecavir USP Impurity D, Entecavir Monohydrate - Impurity D.

What is the molecular formula and molecular weight of Entecavir EP Impurity D?

Entecavir EP Impurity D has the molecular formula C12H15N5O3 and a molecular weight of 277.28 g/mol. Its IUPAC name is 2-amino-9-[(1S,3R,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-1H-purin-6-one.

What is Entecavir EP Impurity D used for?

Entecavir EP Impurity D is supplied as a characterised reference material related to Entecavir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Entecavir EP Impurity D can I order?

We supply Entecavir EP Impurity D in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Entecavir EP Impurity D?

Yes. Every lot of Entecavir EP Impurity D is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Entecavir EP Impurity D be shipped internationally?

Yes. We export Entecavir EP Impurity D worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.