Epirubicin EP Impurity B

Name: Epirubicin EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-025211

About Epirubicin EP Impurity B

Vaqora Chemicals supplies Epirubicin EP Impurity B, a pharmacopeial impurity of Daunorubicin registered under CAS number 21794-55-8. The compound has the formula C21H18O8, corresponding to a molecular weight of 398.4 g/mol. The IUPAC name is (7S,9S)-9-acetyl-6,7,9,11-tetrahydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione. Common synonyms include Daunorubicinone and Daunorubicin EP Impurity A.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 12 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Daunorubicin, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Epirubicin EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Daunorubicin

View every impurity, metabolite and intermediate we list for Daunorubicin.

Daunorubicin impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Epirubicin EP Impurity B
Catalogue No.	VQ-025211
CAS Number	21794-55-8
IUPAC name	(7S,9S)-9-acetyl-6,7,9,11-tetrahydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione
Molecular formula	C₂₁H₁₈O₈
Molecular weight	398.4 g/mol
Exact mass	398.1002
Grade	Reference Standard
HSN code	38229090
InChIKey	YOFDHOWPGULAQF-MQJDWESPSA-N
SMILES	CC(=O)[C@]1(C[C@@H](C2=C(C1)C(=C3C(=C2O)C(=O)C4=C(C3=O)C=CC=C4OC)O)O)O
PubChem CID	83843

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	4 / 8
TPSA	141 Å²
Synonyms	Daunorubicinone, Daunorubicin EP Impurity A, Epirubicin Hydrochloride - Impurity B, Daunorubicin - Impurity A, Daunomycinone, (+)-Daunomycinone, Leukaemomycinone C, rubomycin aglycone, Daunomycin aglicone, (8S,10S)-8-Acetyl-6,8,10,11-tetrahydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione, Daunomycin aglycone, daunomycinaglicone

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H311Toxic in contact with skin
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H331Toxic if inhaled
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation
H340May cause genetic defects
H350May cause cancer
H351Suspected of causing cancer
H360May damage fertility or the unborn child

Precautionary statements: P203, P233, P260, P261, P262, P264, P264 + P265, P270, P271, P272, P280, P284, P301 + P316, P302 + P352, P304 + P340, P305 + P351 + P338, P316, P318, P319, P321, P330, P332 + P317, P333 + P317, P337 + P317

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Epirubicin EP Impurity B?

The CAS Registry Number of Epirubicin EP Impurity B is 21794-55-8. It is also known as Daunorubicinone, Daunorubicin EP Impurity A, Epirubicin Hydrochloride - Impurity B.

What is the molecular formula and molecular weight of Epirubicin EP Impurity B?

Epirubicin EP Impurity B has the molecular formula C21H18O8 and a molecular weight of 398.4 g/mol. Its IUPAC name is (7S,9S)-9-acetyl-6,7,9,11-tetrahydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione.

What is Epirubicin EP Impurity B used for?

Epirubicin EP Impurity B is supplied as a characterised reference material related to Daunorubicin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Epirubicin EP Impurity B can I order?

We supply Epirubicin EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Epirubicin EP Impurity B?

Yes. Every lot of Epirubicin EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Epirubicin EP Impurity B be shipped internationally?

Yes. Epirubicin EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.