Ergotamine EP Impurity B

Name: Ergotamine EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-043464

About Ergotamine EP Impurity B

Ergotamine EP Impurity B (CAS 639-81-6) is a pharmacopeial impurity of Ergotamine offered by Vaqora Chemicals. Formula C33H35N5O5, molecular weight 581.7 g/mol. It is also known as Ergotaminine or Isoergotamine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Ergotamine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Ergotamine EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Ergotamine

View every impurity, metabolite and intermediate we list for Ergotamine.

Ergotamine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Ergotamine EP Impurity B
Catalogue No.	VQ-043464
CAS Number	639-81-6
IUPAC name	(6aR,9S)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.02,6]dodecan-4-yl]-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
Molecular formula	C₃₃H₃₅N₅O₅
Molecular weight	581.7 g/mol
Exact mass	581.2638
Grade	Reference Standard
HSN code	38229090
InChIKey	XCGSFFUVFURLIX-BRMNWJGKSA-N
SMILES	C[C@@]1(C(=O)N2[C@H](C(=O)N3CCC[C@H]3[C@@]2(O1)O)CC4=CC=CC=C4)NC(=O)[C@@H]5CN([C@@H]6CC7=CNC8=CC=CC(=C78)C6=C5)C
PubChem CID	115248

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	3 / 6
TPSA	118 Å²
Synonyms	Ergotaminine, Isoergotamine, Ergotaman-3',6',18-trione, 12'-hydroxy-2'-methyl-5'-(phenylmethyl)-, (5'alpha,8alpha)-, Cornutamine, Ergotaman-3',6',18-trione, 12'-hydroxy-2'-methyl-5'-(phenylmethyl)-, (5'.alpha.,8.alpha.)-, 5'alpha-Benzyl-12'-hydroxy-2'-methyl-3',6',18-trioxo-5alpha-ergotaman

Safety & hazard information (GHS)

Toxic

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H311Toxic in contact with skin
H331Toxic if inhaled
H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P261, P262, P264, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P316, P318, P321, P330, P361 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ergotamine EP Impurity B?

The CAS Registry Number of Ergotamine EP Impurity B is 639-81-6. It is also known as Ergotaminine, Isoergotamine, Ergotaman-3',6',18-trione, 12'-hydroxy-2'-methyl-5'-(phenylmethyl)-, (5'alpha,8alpha)-.

What is the molecular formula and molecular weight of Ergotamine EP Impurity B?

Ergotamine EP Impurity B has the molecular formula C33H35N5O5 and a molecular weight of 581.7 g/mol.

What is Ergotamine EP Impurity B used for?

Ergotamine EP Impurity B is supplied as a characterised reference material related to Ergotamine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ergotamine EP Impurity B can I order?

We supply Ergotamine EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ergotamine EP Impurity B?

Yes. Every lot of Ergotamine EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ergotamine EP Impurity B be shipped internationally?

Yes. Ergotamine EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.