Erlotinib WS

Name: Erlotinib WS
Brand: Vaqora Chemicals
SKU: VQ-007466

About Erlotinib WS

Erlotinib WS (CAS 183321-74-6) is a high-purity reference standard of Erlotinib offered by Vaqora Chemicals. The compound has the formula C22H23N3O4, corresponding to a molecular weight of 393.4 g/mol. Its systematic (IUPAC) name is N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine. Common synonyms include Erlotinib and OSI 744.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Erlotinib, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Erlotinib

View every impurity, metabolite and intermediate we list for Erlotinib.

Erlotinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Erlotinib WS
Catalogue No.	VQ-007466
CAS Number	183321-74-6
IUPAC name	N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine
Molecular formula	C₂₂H₂₃N₃O₄
Molecular weight	393.4 g/mol
Exact mass	393.1689
Grade	Reference Standard
HSN code	38229090
InChIKey	AAKJLRGGTJKAMG-UHFFFAOYSA-N
SMILES	COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC
PubChem CID	176870

Physical properties
Physical form	Solid
LogP (XLogP3)	3.3
H-bond donors / acceptors	1 / 7
TPSA	74.7 Å²
Synonyms	4-[(3-ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline, N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine, Erlotinib, OSI 744, 4-Quinazolinamine, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-, [6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)-amine, (6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl)-(3-ethynyl-phenyl)-amine, Erlotinib free base, Erlotinib Base, Kinome_3317, Erlotinib, Free Base, Erlotinib (INN)

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H351Suspected of causing cancer
H411Toxic to aquatic life with long lasting effects
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P203, P264, P270, P273, P280, P301 + P317, P318, P330, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 183321-74-6

IP/BP/USP

Erlotinib

CAS: 183321-74-6
Formula: C₂₂H₂₃N₃O₄
MW: 393.4 g/mol

VQ-004213

Cell Culture

Erlotinib, cell culture tested

CAS: 183321-74-6
Formula: C₂₂H₂₃N₃O₄
MW: 393.4 g/mol

VQ-046460

Frequently asked questions

What is the CAS number of Erlotinib WS?

The CAS Registry Number of Erlotinib WS is 183321-74-6. It is also known as 4-[(3-ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline, N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine, Erlotinib.

What is the molecular formula and molecular weight of Erlotinib WS?

Erlotinib WS has the molecular formula C22H23N3O4 and a molecular weight of 393.4 g/mol. Its IUPAC name is N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine.

What is Erlotinib WS used for?

Erlotinib WS is supplied as a characterised reference material related to Erlotinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Erlotinib WS can I order?

We supply Erlotinib WS in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Erlotinib WS?

Yes. Every lot of Erlotinib WS is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Erlotinib WS be shipped internationally?

Yes. Erlotinib WS is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.