Estetrol Monohydrate

Name: Estetrol Monohydrate
Brand: Vaqora Chemicals
SKU: VQ-030573

About Estetrol Monohydrate

Vaqora Chemicals supplies Estetrol Monohydrate, a high-purity reference standard of Estriol registered under CAS number 2055649-81-3. The compound has the formula C18H26O5, corresponding to a molecular weight of 322.4 g/mol. Common synonyms include Estetrol hydrous and E4 monohydrate.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this Estriol standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Estriol

View every impurity, metabolite and intermediate we list for Estriol.

Estriol impurities

Specifications & identifiers

Chemical identifiers
Product name	Estetrol Monohydrate
Catalogue No.	VQ-030573
CAS Number	2055649-81-3
IUPAC name	(8R,9S,13S,14S,15R,16R,17R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,15,16,17-tetrol;hydrate
Molecular formula	C₁₈H₂₆O₅
Molecular weight	322.4 g/mol
Exact mass	322.178
Grade	Reference Standard
HSN code	38229090
InChIKey	XRJNAPXFAXBPAM-BVTDNVAGSA-N
SMILES	C[C@]12CC[C@H]3[C@H]([C@@H]1[C@H]([C@H]([C@@H]2O)O)O)CCC4=C3C=CC(=C4)O.O
PubChem CID	135391051

Physical properties
Physical form	Solid
H-bond donors / acceptors	5 / 5
TPSA	81.9 Å²
Synonyms	Estra-1,3,5(10)-triene-3,15alpha,16alpha,17beta-tetrol monohydrate, Estra-1,3,5(10)-triene-3,15,16,17-tetrol, hydrate (1:1), (15alpha,16alpha,17beta)-, Estetrol hydrous, E4 monohydrate, E4 hydrous, Estetrol (hydrate), Estetrol (JAN/USAN)

Safety & hazard information (GHS)

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H351Suspected of causing cancer
H360May damage fertility or the unborn child
H362May cause harm to breast-fed children
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P263, P264, P270, P273, P280, P318, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Estetrol Monohydrate?

The CAS Registry Number of Estetrol Monohydrate is 2055649-81-3. It is also known as Estra-1,3,5(10)-triene-3,15alpha,16alpha,17beta-tetrol monohydrate, Estra-1,3,5(10)-triene-3,15,16,17-tetrol, hydrate (1:1), (15alpha,16alpha,17beta)-, Estetrol hydrous.

What is the molecular formula and molecular weight of Estetrol Monohydrate?

Estetrol Monohydrate has the molecular formula C18H26O5 and a molecular weight of 322.4 g/mol.

What is Estetrol Monohydrate used for?

Estetrol Monohydrate is supplied as a characterised reference material related to Estriol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Estetrol Monohydrate can I order?

We supply Estetrol Monohydrate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Estetrol Monohydrate?

Yes. Every lot of Estetrol Monohydrate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Estetrol Monohydrate be shipped internationally?

Yes. Estetrol Monohydrate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.