Ethyl 2-(Triphenylphosphoranylidene)Propanoate 5717-37-3

Name: Ethyl 2-(Triphenylphosphoranylidene)Propanoate
Brand: Vaqora Chemicals
SKU: VQ-033733

About Ethyl 2-(Triphenylphosphoranylidene)Propanoate

Listed under CAS 5717-37-3, Ethyl 2-(Triphenylphosphoranylidene)Propanoate is an impurity of Sacubitril available from Vaqora Chemicals. Formula C23H23O2P, molecular weight 362.4 g/mol. The IUPAC name is ethyl 2-(triphenyl-lambda5-phosphanylidene)propanoate. It is also known as (Carbethoxyethylidene)triphenylphosphorane or (Carbethoxyethylidine)triphenylphosphorane.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Sacubitril, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sacubitril

View every impurity, metabolite and intermediate we list for Sacubitril.

Sacubitril impurities

Specifications & identifiers

Chemical identifiers
Product name	Ethyl 2-(Triphenylphosphoranylidene)Propanoate
Catalogue No.	VQ-033733
CAS Number	5717-37-3
IUPAC name	ethyl 2-(triphenyl-lambda5-phosphanylidene)propanoate
Molecular formula	C₂₃H₂₃O₂P
Molecular weight	362.4 g/mol
Exact mass	362.1436
Grade	Reference Standard
HSN code	38229090
InChIKey	KZENFXVDPUMQOE-UHFFFAOYSA-N
SMILES	CCOC(=O)C(=P(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)C
PubChem CID	79792

Physical properties
Physical form	Solid
LogP (XLogP3)	4.3
H-bond donors / acceptors	0 / 2
TPSA	26.3 Å²
Synonyms	Ethyl 2-(triphenylphosphoranylidene)propionate, (Carbethoxyethylidene)triphenylphosphorane, Propanoic acid, 2-(triphenylphosphoranylidene)-, ethyl ester, 1-(Ethoxycarbonyl)ethylidenetriphenylphosphorane, (Carbethoxyethylidine)triphenylphosphorane, 1-Carboethoxyethylidenetriphenylphosphorane, 1-Ethoxycarbonyl-ethyliden-phosphoran, Propionic acid, 2-(triphenylphosphoranylidene)-, ethyl ester, Propanoic acid, 2-triphenylphosphoranylidene-, ethyl ester, (1-Ethoxycarbonylethylidene)triphenylphosphorane, 2-(Triphenyl-phosphanylidene)-propionic acid ethyl ester, Ethyl 2-(triphenylphosphoranyl)propanoate

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ethyl 2-(Triphenylphosphoranylidene)Propanoate?

The CAS Registry Number of Ethyl 2-(Triphenylphosphoranylidene)Propanoate is 5717-37-3. It is also known as Ethyl 2-(triphenylphosphoranylidene)propionate, (Carbethoxyethylidene)triphenylphosphorane, Propanoic acid, 2-(triphenylphosphoranylidene)-, ethyl ester.

What is the molecular formula and molecular weight of Ethyl 2-(Triphenylphosphoranylidene)Propanoate?

Ethyl 2-(Triphenylphosphoranylidene)Propanoate has the molecular formula C23H23O2P and a molecular weight of 362.4 g/mol. Its IUPAC name is ethyl 2-(triphenyl-lambda5-phosphanylidene)propanoate.

What is Ethyl 2-(Triphenylphosphoranylidene)Propanoate used for?

Ethyl 2-(Triphenylphosphoranylidene)Propanoate is supplied as a characterised reference material related to Sacubitril. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ethyl 2-(Triphenylphosphoranylidene)Propanoate can I order?

We supply Ethyl 2-(Triphenylphosphoranylidene)Propanoate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ethyl 2-(Triphenylphosphoranylidene)Propanoate?

Yes. Every lot of Ethyl 2-(Triphenylphosphoranylidene)Propanoate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ethyl 2-(Triphenylphosphoranylidene)Propanoate be shipped internationally?

Yes. Ethyl 2-(Triphenylphosphoranylidene)Propanoate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.