Ethyl 7-chloro-4-hydroxyquinoline-3-carboxyla… 16600-22-9

Name: Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate
Brand: Vaqora Chemicals
SKU: VQ-048593

About Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate

Listed under CAS 16600-22-9, Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate is a metabolite or degradation product of Hydroxychloroquine available from Vaqora Chemicals. The compound has the formula C12H10ClNO3, corresponding to a molecular weight of 251.66 g/mol. The IUPAC name is ethyl 7-chloro-4-oxo-1H-quinoline-3-carboxylate. It is also known as 7-chloro-3-ethoxycarbonyl-4(1H)-quinolone.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Hydroxychloroquine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Hydroxychloroquine

View every impurity, metabolite and intermediate we list for Hydroxychloroquine.

Hydroxychloroquine impurities

Specifications & identifiers

Chemical identifiers
Product name	Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate
Catalogue No.	VQ-048593
CAS Number	16600-22-9
IUPAC name	ethyl 7-chloro-4-oxo-1H-quinoline-3-carboxylate
Molecular formula	C₁₂H₁₀ClNO₃
Molecular weight	251.66 g/mol
Exact mass	251.0349
Grade	Reference Standard
HSN code	38229090
InChIKey	XWMCHSWUDMFGSW-UHFFFAOYSA-N
SMILES	CCOC(=O)C1=CNC2=C(C1=O)C=CC(=C2)Cl
PubChem CID	345422

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	1 / 4
TPSA	55.4 Å²
Synonyms	Ethyl 7-chloro-4-oxo-1,4-dihydroquinoline-3-carboxylate, Ethyl 7-chloro-4-hydroxy-3-quinolinecarboxylate, 3-Quinolinecarboxylic acid, 7-chloro-4-hydroxy-, ethyl ester, 7-chloro-3-ethoxycarbonyl-4(1H)-quinolone, ethyl 7-chloro-4-hydroxy-3-quinoline-carboxylate, ethyl 7-chloro-1,4-dihydro-4-oxoquinoline-3-carboxylate, 7-Chloro-4-hydroxy-3-quinolinecarboxylic acid, ethyl ester, 7-chloro-4-hydroxy-quinoline-3-carboxylic acid ethyl ester, 7-chloro-4-hydroxyquinoline-3-carboxylic acid, ethyl ester, 7-Chloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid ethyl ester

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate?

The CAS Registry Number of Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate is 16600-22-9. It is also known as Ethyl 7-chloro-4-oxo-1,4-dihydroquinoline-3-carboxylate, Ethyl 7-chloro-4-hydroxy-3-quinolinecarboxylate, 3-Quinolinecarboxylic acid, 7-chloro-4-hydroxy-, ethyl ester.

What is the molecular formula and molecular weight of Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate?

Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate has the molecular formula C12H10ClNO3 and a molecular weight of 251.66 g/mol. Its IUPAC name is ethyl 7-chloro-4-oxo-1H-quinoline-3-carboxylate.

What is Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate used for?

Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate is supplied as a characterised reference material related to Hydroxychloroquine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate can I order?

We supply Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate?

Yes. Every lot of Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate be shipped internationally?

Yes. We export Ethyl 7-chloro-4-hydroxyquinoline-3-carboxylate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.