Exatecan

Name: Exatecan
Brand: Vaqora Chemicals
SKU: VQ-030647

About Exatecan

Exatecan is a stable isotope labelled analogue related to Camptothecin carrying the CAS registry number 171335-80-1. The compound has the formula C24H22FN3O4, corresponding to a molecular weight of 435.4 g/mol. Common synonyms include exatecan-mesylate and Exatecan free base.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 2 hazard statements. Review the Safety Data Sheet before use.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Exatecan is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies
Fine chemical synthesis

Industries

Related to Camptothecin

View every impurity, metabolite and intermediate we list for Camptothecin.

Camptothecin impurities

Specifications & identifiers

Chemical identifiers
Product name	Exatecan
Catalogue No.	VQ-030647
CAS Number	171335-80-1
IUPAC name	(10S,23S)-23-amino-10-ethyl-18-fluoro-10-hydroxy-19-methyl-8-oxa-4,15-diazahexacyclo[14.7.1.02,14.04,13.06,11.020,24]tetracosa-1,6(11),12,14,16,18,20(24)-heptaene-5,9-dione
Molecular formula	C₂₄H₂₂FN₃O₄
Molecular weight	435.4 g/mol
Exact mass	435.1594
Grade	Reference Standard
HSN code	38229090
InChIKey	ZVYVPGLRVWUPMP-FYSMJZIKSA-N
SMILES	CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C5[C@H](CCC6=C5C(=CC(=C6C)F)N=C4C3=C2)N)O
PubChem CID	151115

Physical properties
Physical form	Solid
LogP (XLogP3)	0.4
H-bond donors / acceptors	2 / 7
TPSA	106 Å²

Safety & hazard information (GHS)

Toxic

Health hazard

Signal word: Danger

Hazard statements

H300Fatal if swallowed
H340May cause genetic defects

Precautionary statements: P203, P264, P270, P280, P301 + P316, P318, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Exatecan?

The CAS Registry Number of Exatecan is 171335-80-1. It is also known as exatecan-mesylate, Exatecan free base, EX-A2683.

What is the molecular formula and molecular weight of Exatecan?

Exatecan has the molecular formula C24H22FN3O4 and a molecular weight of 435.4 g/mol.

What is Exatecan used for?

Exatecan is supplied as a characterised reference material related to Camptothecin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Exatecan can I order?

We supply Exatecan in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Exatecan?

Yes. Every lot of Exatecan is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Exatecan be shipped internationally?

Yes. Exatecan is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.