Topovale

Name: Topovale
Brand: Vaqora Chemicals
SKU: VQ-036105

About Topovale

Topovale (CAS 500214-53-9) is an impurity of Camptothecin offered by Vaqora Chemicals. Its molecular formula is C23H23N3O5 and its molecular weight is 421.4 g/mol. It is also known as ARC-111 or Topoval.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Camptothecin impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Topovale in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. A Safety Data Sheet (SDS) and technical specifications are available on request.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Camptothecin

View every impurity, metabolite and intermediate we list for Camptothecin.

Camptothecin impurities

Specifications & identifiers

Chemical identifiers
Product name	Topovale
Catalogue No.	VQ-036105
CAS Number	500214-53-9
IUPAC name	21-[2-(dimethylamino)ethyl]-16,17-dimethoxy-5,7-dioxa-11,21-diazapentacyclo[11.8.0.02,10.04,8.014,19]henicosa-1(13),2,4(8),9,11,14,16,18-octaen-20-one
Molecular formula	C₂₃H₂₃N₃O₅
Molecular weight	421.4 g/mol
Exact mass	421.1638
Grade	Reference Standard
HSN code	38229090
InChIKey	UVXCXZBZPFCAAJ-UHFFFAOYSA-N
SMILES	CN(C)CCN1C2=C(C=NC3=CC4=C(C=C32)OCO4)C5=CC(=C(C=C5C1=O)OC)OC
PubChem CID	9888428

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	0 / 7
TPSA	73.4 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Topovale?

The CAS Registry Number of Topovale is 500214-53-9. It is also known as ARC-111, Topoval.

What is the molecular formula and molecular weight of Topovale?

Topovale has the molecular formula C23H23N3O5 and a molecular weight of 421.4 g/mol. Its IUPAC name is 21-[2-(dimethylamino)ethyl]-16,17-dimethoxy-5,7-dioxa-11,21-diazapentacyclo[11.8.0.02,10.04,8.014,19]henicosa-1(13),2,4(8),9,11,14,16,18-octaen-20-one.

What is Topovale used for?

Topovale is supplied as a characterised reference material related to Camptothecin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Topovale can I order?

We supply Topovale in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Topovale?

Yes. Every lot of Topovale is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Topovale be shipped internationally?

Yes. We export Topovale worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.