Fexofenadine EP Impurity A (Freebase)

Name: Fexofenadine EP Impurity A (Freebase)
Brand: Vaqora Chemicals
SKU: VQ-006379

About Fexofenadine EP Impurity A (Freebase)

Listed under CAS 76811-98-8, Fexofenadine EP Impurity A (Freebase) is a pharmacopeial impurity of Fexofenadine available from Vaqora Chemicals. The compound has the formula C32H37NO4, corresponding to a molecular weight of 499.6 g/mol. Its systematic (IUPAC) name is 2-[4-[4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butanoyl]phenyl]-2-methylpropanoic acid. Common synonyms include Fexofenadinone and Fexofenadine Ester Impurity.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Fexofenadine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Fexofenadine EP Impurity A (Freebase) is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Fexofenadine

View every impurity, metabolite and intermediate we list for Fexofenadine.

Fexofenadine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Fexofenadine EP Impurity A (Freebase)
Catalogue No.	VQ-006379
CAS Number	76811-98-8
Other CAS	153439-43-1, 2095698-43-2
IUPAC name	2-[4-[4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butanoyl]phenyl]-2-methylpropanoic acid
Molecular formula	C₃₂H₃₇NO₄
Molecular weight	499.6 g/mol
Exact mass	499.2723
Grade	Reference Standard
HSN code	38229090
InChIKey	NGAKDIWPTMPPFP-UHFFFAOYSA-N
SMILES	CC(C)(C1=CC=C(C=C1)C(=O)CCCN2CCC(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)C(=O)O
PubChem CID	9935699

Physical properties
Physical form	Solid
LogP (XLogP3)	3.1
H-bond donors / acceptors	2 / 5
TPSA	77.8 Å²
Synonyms	2-(4-(4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butanoyl)phenyl)-2-methylpropanoic acid, Fexofenadinone, Fexofenadine Ester Impurity, Ketofexofenadine, Fexofenadine Related Compound A (USP), Fexofenadine EP Impurity A, 2-[4-(4-{4-[hydroxy(diphenyl)methyl]piperidin-1-yl}butanoyl)phenyl]-2-methylpropanoic acid, Fexofendine impurityc A, Fexofenadine impurity A CRS, 2-(4-(4-(4-(Hydroxydiphenylmethyl)piperidin-1-yl)butanoyl)phenyl)-2-methylpropanoicacid, 2-[4-[4-[4-[hydroxy(diphenyl)methyl]-1-piperidyl]butanoyl]phenyl]-2-methyl-propanoic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Fexofenadine EP Impurity A (Freebase)?

The CAS Registry Number of Fexofenadine EP Impurity A (Freebase) is 76811-98-8. It is also known as 2-(4-(4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butanoyl)phenyl)-2-methylpropanoic acid, Fexofenadinone, Fexofenadine Ester Impurity.

What is the molecular formula and molecular weight of Fexofenadine EP Impurity A (Freebase)?

Fexofenadine EP Impurity A (Freebase) has the molecular formula C32H37NO4 and a molecular weight of 499.6 g/mol. Its IUPAC name is 2-[4-[4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butanoyl]phenyl]-2-methylpropanoic acid.

What is Fexofenadine EP Impurity A (Freebase) used for?

Fexofenadine EP Impurity A (Freebase) is supplied as a characterised reference material related to Fexofenadine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Fexofenadine EP Impurity A (Freebase) can I order?

We supply Fexofenadine EP Impurity A (Freebase) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Fexofenadine EP Impurity A (Freebase)?

Yes. Every lot of Fexofenadine EP Impurity A (Freebase) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Fexofenadine EP Impurity A (Freebase) be shipped internationally?

Yes. Fexofenadine EP Impurity A (Freebase) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.