Gemcitabine HCl

Name: Gemcitabine HCl
Brand: Vaqora Chemicals
SKU: VQ-004214

About Gemcitabine HCl

Listed under CAS 122111-03-9, Gemcitabine HCl is an anticancer API available from Vaqora Chemicals in Pharma grade. Its molecular formula is C9H12ClF2N3O4 and its molecular weight is 299.66 g/mol. Systematically, it is named 4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one. Hydrochloride. Alternative names: LY188011 hydrochloride and 2'-deoxy-2',2'-difluorocytidine hydrochloride.

The material typically appears as a white or almost white crystalline powder. Store sealed in a dry, well-ventilated location away from incompatible materials. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

This API belongs to our oncology APIs portfolio and is supplied to Pharma specifications for formulators, contract manufacturers and generic drug developers. Buyers come mainly from pharmaceutical manufacturing.

Vaqora Chemicals supplies Gemcitabine HCl in 1 kg, 5 kg and 25 kg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmaceutical formulation
Generic drug development

Industries

Related to Gemcitabine

View every impurity, metabolite and intermediate we list for Gemcitabine.

Gemcitabine impurities

Specifications & identifiers

Chemical identifiers
Product name	Gemcitabine HCl
Catalogue No.	VQ-004214
CAS Number	122111-03-9
IUPAC name	4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one;hydrochloride
Molecular formula	C₉H₁₂ClF₂N₃O₄
Molecular weight	299.66 g/mol
Exact mass	299.0484
Grade	Pharma
HSN code	2933
InChIKey	OKKDEIYWILRZIA-OSZBKLCCSA-N
SMILES	C1=CN(C(=O)N=C1N)[C@H]2C([C@@H]([C@H](O2)CO)O)(F)F.Cl
PubChem CID	60749

Physical properties
Physical form	Powder
Appearance	White or almost white crystalline powder
H-bond donors / acceptors	4 / 6
TPSA	108 Å²
Synonyms	LY188011 hydrochloride, 2'-Deoxy-2',2'-difluorocytidine monohydrochloride, 2'-deoxy-2',2'-difluorocytidine hydrochloride, Gemcitabine (as hydrochloride), Cytidine, 2'-deoxy-2',2'-difluoro-, monohydrochloride, Gemcitabine HCI, 2',2'-Difluorodeoxycytidine monohydrochloride, 2'Deoxy-2',2'-Difluorocytidine, Hydrochloride, 1-(2-Oxo-4-amino-1,2-dihydropyrimidin-1-yl)-2-deoxy-2,2-difluororibose, hydrochloride, Difluorodeoxycytidine Hydrochloride, Gemzar (TN), Gemcitabine (Hydrochloride)

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H340May cause genetic defects
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P264, P264 + P265, P270, P280, P301 + P317, P302 + P352, P305 + P351 + P338, P317, P318, P321, P330, P332 + P317, P337 + P317, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 122111-03-9

Gemcitabine hydrochloride, ≥98%

CAS: 122111-03-9
Formula: C₉H₁₂ClF₂N₃O₄
MW: 299.66 g/mol

VQ-011976

Frequently asked questions

What is the CAS number of Gemcitabine HCl?

The CAS Registry Number of Gemcitabine HCl is 122111-03-9. It is also known as LY188011 hydrochloride, 2'-Deoxy-2',2'-difluorocytidine monohydrochloride, 2'-deoxy-2',2'-difluorocytidine hydrochloride.

What is the molecular formula and molecular weight of Gemcitabine HCl?

Gemcitabine HCl has the molecular formula C9H12ClF2N3O4 and a molecular weight of 299.66 g/mol.

What is Gemcitabine HCl used for?

Gemcitabine HCl is supplied as a characterised reference material related to Gemcitabine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Gemcitabine HCl can I order?

We supply Gemcitabine HCl in Pharma grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Gemcitabine HCl?

Yes. Every lot of Gemcitabine HCl is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Gemcitabine HCl be shipped internationally?

Yes. Gemcitabine HCl is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.